ArticleHIV/AIDS (Auckland, N.Z.)2020
Alarm Clock-Based Reminder for Improving Low Adherence on Option B Plus Antiretroviral Therapy Among HIV Positive Pregnant and Lactating Mothers in Northern Ethiopia.
Article in HIV/AIDS (Auckland, N.Z.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.
- Adherence to option B + antiretroviral therapy and associated factors in pregnant and breastfeeding women in Sub-Saharan Africa: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Interventions to improve antiretroviral adherence in HIV-infected pregnant women: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Effect of male partners' involvement and support on reproductive, maternal and child health and well-being in East Africa: A scoping review.Health science reports · 2024Article
- Highly active antiretroviral therapy adherence among HIV-POSITIVE women in Southern Ethiopia.Frontiers in pharmacology · 2024Article
- Adherence to option B+ PMTCT program and its predictors among HIV-positive women in Ethiopia. A systematic review and meta-analysis.Health science reports · 2023Article
- Factors associated with antiretroviral therapy adherence among adolescents living with HIV in the era of isoniazid preventive therapy as part of HIV care.PLOS global public health · 2022Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOption B plus antiretroviral therapy (ART) is an approach used to eliminate new Human Immune Deficiency Virus (HIV) infections among infants. Considering the high adherence on Option B plus ART in HIV positive mothers is a crucial part in preventing mother-to-child transmission HIV. Therefore, this study was performed to assess the status of adherence and factors related to Option B plus ART.
methodsA cross-sectional study design was conducted in Eastern zone of Tigrai Region from January to February 2017. Data were collected by using pre-tested structured interviewer-administered questionnaire from 350 participants selected using simple random sampling. Descriptive and binary logistic regression was done during analysis.
resultsThe overall good adherence status of Option B plus ART among pregnant and lactating mothers was 67.3% [62.3-72.3%]. Attending formal education (AOR=2.78, 95% CI 1.52-5.07), traveling for <1 hour to reach health facility (AOR=2.03, 95% CI 1.19-3.44), (CD4) count <350 cells/mm3 (AOR=2.3, 95% CI 1.33-3.95), starting their Option B plus during pregnancy (AOR= 2.08, 95% CI 1.08-3.97), taking one pill per day (AOR=2.12, 95% CI 1.25-3.58), using a clock as a reminder (AOR=2.51, 95% CI 1.3-4.86), and having good male involvement (AOR=2.91, 95% CI 1.64-5.16) were associated with good level of adherence for Option B plus ART treatment.
conclusionOur study revealed that the level of good adherence is low compared with the national target. Therefore, addressing the low adherence of Option B plus ART requires a policy response, such as efforts to enhance male partner involvement and better service accessibility in Prevention of Mother-to-Child Transmission (PMTCT) program. Moreover, health care providers and policymakers need to maximaze their efforts on HIV positive pregnant and lactating mothers using a clock as a reminder.
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