Evidence map›Paper›PMID 33177880›Full record

ArticleClinical epidemiology2020

Long-Term Risk of Stroke and Poststroke Outcomes in Patients with Heart Failure: Two Nationwide Studies.

Ying-Hsuan Tai, Chuen-Chau Chang, Chun-Chieh Yeh, Li-Chin Sung, Chaur-Jong Hu, Yih-Giun Cherng, Ta-Liang Chen, Chien-Chang Liao

Open access · goldAbstract read
In one paragraph

Article in Clinical epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Heart Failure and Stroke: A Narrative Review.Journal of clinical medicine · 2025
    Review
  5. Stroke incidence in heart failure and atrial fibrillation: a population-based retrospective cohort study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ying-Hsuan Tai *Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Chuen-Chau ChangDepartment of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0002-9603-5456
Chun-Chieh YehDepartment of Surgery, China Medical University Hospital, Taichung, Taiwan.
Li-Chin SungDivision of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.ORCID 0000-0001-6292-7117
Chaur-Jong HuDepartment of Neurology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
Yih-Giun CherngDepartment of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.ORCID 0000-0002-0201-4380
Ta-Liang Chen *Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chien-Chang Liao *Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0001-6694-0730
Taipei Medical University-Shuang Ho Hospital · TWChina Medical University · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the long-term risk of stroke and poststroke adverse outcomes in patients with heart failure (HF).

methodsWe used research data from Taiwan's National Health Insurance Program from 2000 to 2005 and identified 20,072 adults aged ≥30 years who were newly diagnosed with HF. Frequency matching based on age and sex was used to select a comparison cohort consisting of 80,288 adults without HF. Events of incident stroke were identified from medical claims during the 2000-2013 follow-up period. The adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of the association of stroke with HF were calculated with a multiple Cox proportional hazard model. Another nested stroke cohort study of 480,604 hospitalized stroke patients determined the adjusted odds ratios (ORs) and 95% CIs for adverse events after stroke in patients with and without HF between 2000 and 2009.

resultsCompared with the non-HF cohort, HF patients had an increased risk of stroke (HR 2.32, 95% CI 2.21-2.43), including ischemic stroke and hemorrhagic stroke. The association between HF and stroke was significant in both sexes and in patients in all age groups and with various medical conditions. Previous HF was associated with poststroke mortality (OR 1.40, 95% CI 1.31-1.50), pneumonia (OR 1.33, 95% CI 1.28-1.38), and septicemia (OR 1.30, 95% CI 1.23-1.37).

conclusionHF was associated with a higher risk of stroke, and patients with HF had more complications and greater mortality after stroke.

Indexed as

adverse outcomeheart failureriskstroke

Identifiers

PMID33177880
PMCPMC7652062
OpenAlexW3095073192

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.