Evidence map›Paper›PMID 33177845›Full record

ReviewInfection and drug resistance2020

Risk Factors of Extended-Spectrum Beta-Lactamases-Producing

Stéphanie Larramendy, Valentine Deglaire, Paul Dusollier, Jean-Pascal Fournier, Jocelyne Caillon, François Beaudeau, Leïla Moret

Abstract readReview
In one paragraph

Review in Infection and drug resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. One Health Determinants ofInternational journal of molecular sciences · 2023
    Pooled it
  2. Observational
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  12. Review
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  16. Exploring the TEM β-Lactamase inInfection and drug resistance · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Prevalence and risk factors of extended-spectrum beta-lactamase producing E. coli causing urinary tract infections in Iceland during 2012-2021.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stéphanie LarramendyDepartment of General Practice, Faculty of Medicine, University of Nantes, Nantes 44000, France.ORCID 0000-0003-0639-6694
Valentine DeglaireDepartment of General Practice, Faculty of Medicine, University of Nantes, Nantes 44000, France.
Paul DusollierDepartment of General Practice, Faculty of Medicine, University of Nantes, Nantes 44000, France.
Jean-Pascal FournierDepartment of General Practice, Faculty of Medicine, University of Nantes, Nantes 44000, France.ORCID 0000-0002-9971-0672
Jocelyne CaillonIRS 2 Laboratoire de Thérapeutique Expérimentale et Clinique des Infections, EA3826, University of Nantes, Nantes 44400, France.
François BeaudeauBIOEPAR, INRA, Oniris, Nantes 44307, France.
Leïla MoretPublic Health Department, CHU Nantes, Saint-Jacques Hospital, Nantes 44093, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe prevalence of extended-spectrum beta-lactamase-producing

methodsWe searched the MEDLINE, Cochrane Library, Embase and Web of Science databases without language or date restriction up to March 2019. Two independent reviewers selected studies with quantified risk factors for CA-UTI due to ESBL-EC, and assessed their quality using the Newcastle-Ottawa Scale.

resultsAmong the 5,597 studies identified, 16 observational studies (n=12,138 patients) met the eligibility criteria. The included studies were performed in various countries, and 14/16 were published after 2012. The most relevant risk factors for CA-UTI due to ESBL-EC identified were prior use of antibiotics (odds ratio (OR) from 2.2 to 21.4), previous hospitalization (OR: 1.7 to 3.9), and UTI history (OR: 1.3 to 3.8). Two risk factors were related to environmental contamination: travelling abroad, and swimming in freshwater.

conclusionOur findings could allow adapting empiric antibiotic treatments according to the patient profile. Further studies are needed to quantify the relationships between CA-UTI due to ESBL-EC and the environment.

Indexed as

beta-lactam resistancecommunity-acquired infectionenterobacteria infectionmulti-drug resistant bacteriarisk factorsystematic review

Identifiers

PMID33177845
PMCPMC7650195

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.