Evidence map›Paper›PMID 33177749›Full record

ArticleStat2019

Logistic regression error-in-covariate models for longitudinal high-dimensional covariates.

Hyung Park, Seonjoo Lee

Abstract read
In one paragraph

Article in Stat, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hyung ParkDivision of Biostatistics, Department of Population Health, New York University, New York, NY 10016.ORCID 0000-0002-8994-9583
Seonjoo LeeResearch Foundation for Mental Hygiene, Inc., New York, NY 10032.ORCID 0000-0003-3177-6357

Funding

Statistical Methods for Neural Mechanisms Mediating Cognitive System in Mental Health ResearchK01AG051348 · NIA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI LEE, SEONJOO · 2015 to 2018
$526k
NIA NIH HHS K01 AG051348
6 · The paper itself

Abstract

We consider a logistic regression model for a binary response where part of its covariates are subject-specific random intercepts and slopes from a large number of longitudinal covariates. These random effect covariates must be estimated from the observed data, and therefore, the model essentially involves errors in covariates. Because of high dimension and high correlation of the random effects, we employ longitudinal principal component analysis to reduce the total number of random effects to some manageable number of random effects. To deal with errors in covariates, we extend the conditional-score equation approach to this moderate dimensional logistic regression model with random effect covariates. To reliably solve the conditional-score equations in moderate/high dimension, we apply a majorization on the first derivative of the conditional-score functions and a penalized estimation by the smoothly clipped absolute deviation. The method was evaluated through a set of simulation studies and applied to a data set with longitudinal cortical thickness of 68 regions of interest to identify biomarkers that are related to dementia transition.

Indexed as

conditional-score equationserrors in covariateslongitudinal functional principal component analysis

Identifiers

PMID33177749
PMCPMC7654973

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.