Evidence map›Paper›PMID 33177713›Full record

ArticleNature2020

Transcriptome and translatome co-evolution in mammals.

Zhong-Yi Wang, Evgeny Leushkin, Angélica Liechti, Svetlana Ovchinnikova, Katharina Mößinger, Thoomke Brüning, Coralie Rummel, Frank Grützner, Margarida Cardoso-Moreira, Peggy Janich and 7 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed
22.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 220 citations in OpenAlex.

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  4. Testicular mRNA-LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  6. The molecular evolution of vertebrate organs.Nature ecology & evolution · 2026
    Review
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Zhong-Yi Wang *Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Evgeny Leushkin *Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany. e.leushkin@zmbh.uni-heidelberg.de.
Angélica LiechtiCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-0166-0639
Svetlana OvchinnikovaCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Katharina MößingerCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Thoomke BrüningCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.
Coralie RummelCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Frank GrütznerRobinson Research Institute, School of Biological Sciences, University of Adelaide, Adelaide, South Australia, Australia.ORCID http://orcid.org/0000-0002-3088-7314
Margarida Cardoso-MoreiraCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6639-3597
Peggy JanichCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-1045-7365
David GatfieldCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-5114-2824
Boubou DiagouragaInstitute of Human Genetics, Centre National de la Recherche Scientifique, Université de Montpellier, Montpellier, France.
Bernard de MassyInstitute of Human Genetics, Centre National de la Recherche Scientifique, Université de Montpellier, Montpellier, France.
Mark E GillFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Antoine H F M PetersFriedrich Miescher Institute for Biomedical Research, Basel, Switzerland.ORCID http://orcid.org/0000-0002-0311-1887
Simon AndersCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-4868-1805
Henrik KaessmannCenter for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBH Alliance, Heidelberg, Germany. h.kaessmann@zmbh.uni-heidelberg.de.ORCID http://orcid.org/0000-0001-7563-839X
Heidelberg University · DEUniversity of Lausanne · CHCentre National de la Recherche Scientifique · FRFriedrich Miescher Institute · CHThe University of Adelaide · AUUniversité de Montpellier · FRUniversity of Basel · CH

Funding

European Research Council 615253Swiss National Science Foundation 146293
6 · The paper itself

Abstract

Gene-expression programs define shared and species-specific phenotypes, but their evolution remains largely uncharacterized beyond the transcriptome layer

Indexed as

Evolution, MolecularProtein BiosynthesisAnimalsBrainChickensFemaleGenes, X-LinkedHumansLiverMacacaMaleMammalsMiceOpossumsOrgan SpecificityPlatypus

Identifiers

PMID33177713
PMCPMC7116861
OpenAlexW3101518221

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.