ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Prognosis of conventional vs. high-frequency ventilation for congenital diaphragmatic hernia: a retrospective cohort study.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Comparison of conventional mechanical ventilation and high-frequency oscillatory ventilation in congenital diaphragmatic hernias: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Perioperative biventricular function in congenital diaphragmatic hernia: a three-dimensional echocardiographic study.Pediatric research · 2026Article
- Application of neurally adjusted ventilatory assist (NAVA): a narrative review.Journal of thoracic disease · 2025Review
- Clinical characteristics and outcomes of neonates with congenital diaphragmatic hernia at the Vietnam National Children's Hospital: a retrospective observational study.BMC pediatrics · 2025Observational
- Association between initial ventilation mode and hospital outcomes for severe congenital diaphragmatic hernia.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- The role of extracorporeal life support and timing of repair in infants with congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- Right to left ventricular volume ratio is associated with mortality in congenital diaphragmatic hernia.Pediatric research · 2023Article
- Post-natal prognostic factors in CDH: experience of 11 years in a referral center in Brazil.Clinics (Sao Paulo, Brazil) · 2023Article
- Congenital diaphragmatic hernia survival in an English regional ECMO center.World journal of pediatric surgery · 2023Article
- Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022Review
- Best pre-ductal PaOPediatric surgery international · 2021Article
- Respiratory Support of Infants With Congenital Diaphragmatic Hernia.Frontiers in pediatrics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 11 institutions in 1 country.
Funding
Abstract
objectiveTo determine the appropriate initial ventilatory mode for neonatal congenital diaphragmatic hernia (CDH) by comparing patient prognosis following conventional mechanical ventilation (CMV) versus high-frequency oscillatory ventilation (HFO). STUDY
designThis multicenter retrospective cohort study was performed at 15 participating hospitals in Japan between 2011 and 2016. The 328 eligible CDH infants were classified into CMV (n = 78) and HFO groups (n = 250) to compare mortality and incidence of bronchopulmonary dysplasia (BPD). Propensity score matching was applied to reduce confounding by indication.
resultWhile crude mortality was significantly higher in the HFO than the CMV group, adjusted odds ratio (OR) did not show significant difference in mortality between groups (OR of HFO group: 0.98, 95% confidence interval (CI): 0.57-1.67). Adjusted OR of BPD incidence showed no significant difference between groups (OR of HFO group: 1.66, 95%CI: 0.50-5.49).
conclusionInitial ventilatory mode in CDH patients, whether CMV or HFO, does not affect prognosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.