Evidence map›Paper›PMID 33177645›Full record

ArticleCommunications biology2020

Co-activation of Akt, Nrf2, and NF-κB signals under UPR

Wenjie Huang, Chen-Chung Liao, Yijie Han, Junyan Lv, Ming Lei, Yangyang Li, Qingyun Lv, Dong Dong, Shuyi Zhang, Yi-Husan Pan and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. HSPA5 overexpression predicts poor prognosis and drives radioresistance and metastasis in nasopharyngeal carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
  3. Harnessing Evolution and Biomimetics to Enhance Planetary Health: Kidney Insights.Journal of the American Society of Nephrology : JASN · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Wenjie HuangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.ORCID 0000-0001-5509-1470
Chen-Chung LiaoProteomics Research Center, National Yang-Ming University, Taipei, 11221, Taiwan.
Yijie HanUniversity of Chinese Academy of Sciences, Beijing, 100049, China.
Junyan LvKey Laboratory of Brain Functional Genomics (Ministry of Education and Shanghai), Institute of Brain Functional Genomics, School of Life Sciences and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, 200062, China.
Ming LeiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Yangyang LiKey Laboratory of Brain Functional Genomics (Ministry of Education and Shanghai), Institute of Brain Functional Genomics, School of Life Sciences and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, 200062, China.
Qingyun LvKey Laboratory of Brain Functional Genomics (Ministry of Education and Shanghai), Institute of Brain Functional Genomics, School of Life Sciences and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, 200062, China.
Dong DongShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China.
Shuyi ZhangCollege of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, 110866, China.
Yi-Husan PanKey Laboratory of Brain Functional Genomics (Ministry of Education and Shanghai), Institute of Brain Functional Genomics, School of Life Sciences and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, 200062, China. yihsuanp@gmail.com.ORCID 0000-0001-5156-9887
Jian LuoShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, 200241, China. jluo@bio.ecnu.edu.cn.ORCID 0000-0003-3583-0154
East China Normal University · CNNational Yang Ming Chiao Tung University · TWShenyang Agricultural University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bats hibernate to survive stressful conditions. Examination of whole cell and mitochondrial proteomes of the liver of Myotis ricketti revealed that torpid bats had endoplasmic reticulum unfolded protein response (UPR

Indexed as

AnimalsChiropteraEndoplasmic ReticulumEndoplasmic Reticulum-Associated DegradationEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressHibernationLiverMaleMiceMice, Inbred ICRNF-E2-Related Factor 2NF-kappa BProto-Oncogene Proteins c-aktEndoplasmic Reticulum Chaperone BiPHspa5 protein, mouseNF-E2-Related Factor 2NF-kappa BProto-Oncogene Proteins c-akt

Identifiers

PMID33177645
PMCPMC7658203
OpenAlexW3106477034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.