Evidence map›Paper›PMID 33177614›Full record

ArticleScientific reports2020

Predictive modeling of proliferative vitreoretinopathy using automated machine learning by ophthalmologists without coding experience.

Fares Antaki, Ghofril Kahwati, Julia Sebag, Razek Georges Coussa, Anthony Fanous, Renaud Duval, Mikael Sebag

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Comparing code-free and bespoke deep learning approaches in ophthalmology.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Review
  8. Article
  9. Article
  10. A Prediction Nomogram for Recurrent Retinal Detachment.Risk management and healthcare policy · 2023
    Article
  11. Deep learning for ultra-widefield imaging: a scoping review.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  12. Article
  13. Article
  14. Evaluating an automated machine learning model that predicts visual acuity outcomes in patients with neovascular age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Fares AntakiDepartment of Ophthalmology, Université de Montréal, Montreal, QC, Canada.ORCID 0000-0001-6679-7276
Ghofril KahwatiInstitut National des Sciences Appliquées de Toulouse (INSA Toulouse), Toulouse, France.
Julia SebagDepartment of Ophthalmology, Université de Montréal, Montreal, QC, Canada.
Razek Georges CoussaDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Anthony FanousFaculty of Medicine, McGill University, Montreal, QC, Canada.
Renaud DuvalDepartment of Ophthalmology, Université de Montréal, Montreal, QC, Canada.
Mikael SebagDepartment of Ophthalmology, Université de Montréal, Montreal, QC, Canada. sebag.mikael@gmail.com.
Hôpital Maisonneuve-Rosemont · CACentre Hospitalier de l’Université de Montréal · CAInstitut National des Sciences Appliquées de Toulouse · FRMcGill University · CAUniversité de Montréal · CAUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to assess the feasibility of machine learning (ML) algorithm design to predict proliferative vitreoretinopathy (PVR) by ophthalmologists without coding experience using automated ML (AutoML). The study was a retrospective cohort study of 506 eyes who underwent pars plana vitrectomy for rhegmatogenous retinal detachment (RRD) by a single surgeon at a tertiary-care hospital between 2012 and 2019. Two ophthalmologists without coding experience used an interactive application in MATLAB to build and evaluate ML algorithms for the prediction of postoperative PVR using clinical data from the electronic health records. The clinical features associated with postoperative PVR were determined by univariate feature selection. The area under the curve (AUC) for predicting postoperative PVR was better for models that included pre-existing PVR as an input. The quadratic support vector machine (SVM) model built using all selected clinical features had an AUC of 0.90, a sensitivity of 63.0%, and a specificity of 97.8%. An optimized Naïve Bayes algorithm that did not include pre-existing PVR as an input feature had an AUC of 0.81, a sensitivity of 54.3%, and a specificity of 92.4%. In conclusion, the development of ML models for the prediction of PVR by ophthalmologists without coding experience is feasible. Input from a data scientist might still be needed to tackle class imbalance-a common challenge in ML classification using real-world clinical data.

Indexed as

Machine LearningAgedAlgorithmsDiagnosis, Computer-AssistedFemaleHumansMaleMiddle AgedOphthalmologistsPostoperative ComplicationsRetinal DetachmentRetrospective StudiesRisk FactorsVitrectomyVitreoretinopathy, Proliferative

Identifiers

PMID33177614
PMCPMC7658348
OpenAlexW3105833805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.