ArticleScientific reports2020
Utility of shape evolution and displacement in the classification of chronic multiple sclerosis lesions.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Dimethyl fumarate preserves brainstem and cervical spinal cord integrity in radiologically isolated syndrome.Journal of neurology · 2024Trial
- Convolutional neural network based system for fully automatic FLAIR MRI segmentation in multiple sclerosis diagnosis.Scientific reports · 2025Article
- Current Clinical Applications of Structural MRI in Neurological Disorders.Journal of clinical neurology (Seoul, Korea) · 2025Review
- Dynamic Expansion and Contraction of Multiple Sclerosis T2-Weighted Hyperintense Lesions Are Present below the Threshold of Visual Perception.AJNR. American journal of neuroradiology · 2025Article
- Transforming grayscale MRI images to color utilizing generative artificial intelligence to better understand multiple sclerosis.Journal of central nervous system disease · 2025Article
- Chronic active lesions preferentially localize in watershed territories in multiple sclerosis.Annals of clinical and translational neurology · 2024Article
- Imaging the brain: diagnosis aided by structural features on neuroimaging studies.Eye (London, England) · 2024Review
- T2-fluid attenuated inversion recovery fat-suppressed mismatch in the identification and characterization of lesions related to radiologically isolated syndrome.BJR case reports · 2024Article
- Radiologically isolated syndrome in the spectrum of multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024Review
- The diagnostic value of the central vein sign in radiologically isolated syndrome.Annals of clinical and translational neurology · 2024Article
- Chronic active lesions in multiple sclerosis: classification, terminology, and clinical significance.Therapeutic advances in neurological disorders · 2024Review
- The radiologically isolated syndrome: revised diagnostic criteria.Brain : a journal of neurology · 2023Article
- Neuroimaging to monitor worsening of multiple sclerosis: advances supported by the grant for multiple sclerosis innovation.Frontiers in neurology · 2023Review
- Lesion size and shape in central vein sign assessment for multiple sclerosis diagnosis: An in vivo and postmortem MRI study.Multiple sclerosis (Houndmills, Basingstoke, England) · 2022Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The accurate recognition of multiple sclerosis (MS) lesions is challenged by the high sensitivity and imperfect specificity of MRI. To examine whether longitudinal changes in volume, surface area, 3-dimensional (3D) displacement (i.e. change in lesion position), and 3D deformation (i.e. change in lesion shape) could inform on the origin of supratentorial brain lesions, we prospectively enrolled 23 patients with MS and 11 patients with small vessel disease (SVD) and performed standardized 3-T 3D brain MRI studies. Bayesian linear mixed effects regression models were constructed to evaluate associations between changes in lesion morphology and disease state. A total of 248 MS and 157 SVD lesions were studied. Individual MS lesions demonstrated significant decreases in volume < 3.75mm
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