ArticleScientific reports2020
Quantitative measures of vortex veins in the posterior pole in eyes with pachychoroid spectrum diseases.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 47 citations in OpenAlex.
- Pentraxin-3 and Lipocalin-2 are decreased in patients with uveal effusion syndrome.International ophthalmology · 2025Trial
- Anterior Suprachoroidal Fluid Following Photodynamic Therapy for Chronic CSC: An Anterior-Segment Optical Coherence Tomography Study.Ophthalmology and therapy · 2026Article
- Non-indocyanine green angiography non-invasive differentiating features in the differential diagnosis of pachychoroid neovasculopathy and neovascular age-related macular degeneration: a sensitivity-specificity study.Eye (London, England) · 2025Article
- Reduction in choroidal thickness associated with the progression of pachychoroid spectrum diseases.Japanese journal of ophthalmology · 2025Article
- OCT and OCTA quantitative metrics for polypoidal choroidal vasculopathy.BMJ open ophthalmology · 2025Review
- Article
- Structural changes in vortex vein ampullae in eyes with pachychoroid-spectrum disorder.Scientific reports · 2025Article
- Preferential Locations of Polypoidal Lesions and Adjacent Pigment Epithelium Detachments in Polypoidal Choroidal Vasculopathy in a Japanese Population.Investigative ophthalmology & visual science · 2025Article
- Quantitative analysis of choroidal vascular structures and anatomical changes in pachychoroid spectrum diseases using ultra-widefield SS-OCTA.Scientific reports · 2025Article
- Influence of vortex vein engorgement for photodynamic therapy in central serous chorioretinopathy.Scientific reports · 2024Article
- Clinical implications of choroidal vascular brightness using ultra-widefield indocyanine green angiography in polypoidal choroidal vasculopathy.Scientific reports · 2023Article
- Vortex vein engorgement and different shapes of venous drainage systems in polypoid choroidal vasculopathy vs. age‑related macular degeneration on indocyanine green angiography.Experimental and therapeutic medicine · 2023Article
- Quadrant laser photocoagulation trial to ameliorate choroidal congestion in central serous chorioretinopathy.Japanese journal of ophthalmology · 2023Article
- Retinal Pigment Epithelial Abnormality and Choroidal Large Vascular Flow Imbalance Are Associated with Choriocapillaris Flow Deficits in Age-Related Macular Degeneration in Fellow Eyes.Journal of clinical medicine · 2023Article
- Pathomechanisms in central serous chorioretinopathy: A recent update.International journal of retina and vitreous · 2023Review
- Polypoidal Choroidal Vasculopathy: An Update on Diagnosis and Treatment.Clinical ophthalmology (Auckland, N.Z.) · 2023Review
- A Comparative Study of Choroidal Vascular and Structural Characteristics of Typical Polypoidal Choroidal Vasculopathy and Polypoidal Choroidal Neovascularization: OCTA-Based Evaluation of Intervortex Venous Anastomosis.Diagnostics (Basel, Switzerland) · 2022Article
- Natural Course of Pachychoroid Pigment Epitheliopathy.Ophthalmology science · 2022Article
- A new insight into pachychoroid diseases: Remodeling of choroidal vasculature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Review
- Relationship between Pachychoroid and Polypoidal Choroidal Vasculopathy.Journal of clinical medicine · 2022Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polypoidal lesions (PNV), and pachychoroid neovasculopathy with polypoidal lesions (polypoidal choroidal vasculopathy: PCV). In a retrospective case series of 94 eyes with CSC, 60 eyes with PNV and 57 with PCV, we binarized en face optical coherence tomography (OCT) images of choroidal vortex veins and analyzed the mean diameter of vortex veins. The presence of anastomosis between the superior and inferior vortex veins and central choroidal thickness (CCT) were also evaluated using OCT images. CSC showed significantly larger mean diameter of vortex veins than PCV (P < 0.05). Anastomosis between superior and inferior vortex veins was observed in over 90% of eyes with each pachychoroid spectrum disease. The patients with CSC were the youngest, followed by PNV patients, and then patients with PCV. The largest CCT values were observed in CSC eyes, followed by PNV eyes, and then PCV eyes. CCT correlated with the mean diameter of vortex veins (rs = 0.51, P < 0.01). These findings suggest that congestion of vortex veins might show gradual amelioration corresponding to the development of anastomosis between the superior and inferior vortex veins during the course of progression of pachychoroid spectrum diseases. Moreover, the mean diameter of vortex veins can be used as a parameter indicating choroidal congestion.
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