ArticleJournal of the Chinese Medical Association : JCMA2021
Physician decision support system for idiopathic sudden sensorineural hearing loss patients.
Article in Journal of the Chinese Medical Association : JCMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Early hearing improvement predicts complete recovery in sudden hearing loss.Journal of the Chinese Medical Association : JCMA · 2026Article
- A novel audiogram model for predicting the prognosis of sudden sensorineural hearing loss.Journal of the Chinese Medical Association : JCMA · 2025Article
- Optimizing age-related hearing risk predictions: an advanced machine learning integration with HHIE-S.BioData mining · 2023Article
- Using artificial intelligence algorithms to predict the overall survival of hemodialysis patients during the COVID-19 pandemic: A prospective cohort study.Journal of the Chinese Medical Association : JCMA · 2023Article
- Interpretable Clinical Decision Support System for Audiology Based on Predicted Common Audiological Functional Parameters (CAFPAs).Diagnostics (Basel, Switzerland) · 2022Article
- Expert validation of prediction models for a clinical decision-support system in audiology.Frontiers in neurology · 2022Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic sudden sensorineural hearing loss (ISSNHL) is an emergency disease, and its pathogenesis is still largely unknown, making it difficult to diagnose and develop a therapeutic strategy. To predict the treatment outcomes and further customize the treatment strategy, we used a physician decision support system that incorporates complex information from electronic health records. We first developed the infrastructure of the physician decision support system, including an integrated data warehouse and an automatic data de-identification workflow.
methodsWe next conducted a cohort study to evaluate the treatment outcomes of 757 ISSNHL patients using the modified Siegel's criteria. The complete recovery (<25 dB) as a hearing outcome for ISSNHL patients was compared based on pretreatment hearing grades and disease onset with adjusted for age and sex after treatment initiation.
resultsThe results showed that a complete recovery hearing outcome based on pretreatment hearing grades and disease onset in consideration of age and sex was associated with a low risk of pretreatment hearing Grade 2 (26-45 dB) (adjusted odds ratio 12.3, 95% confidence interval [CI]: 4.8-31.3) and disease onset ≤7 days (adjusted odds ratio 13.9, 95% CI: 4.2-45.8), respectively. Hearing recovery outcomes among complete recovery and noncomplete recovery (>25 dB) subjects according to pretreatment hearing grades were 32.9% (Grade 2 or 26-45 dB HL), 25.4% (Grade 3 or 46-75 dB HL), 31.1% (Grade 4 or 76-90 dB), and 4.5% (Grade 5, or >90 dB HL) (p < 0.0001). Patients with pretreatment hearing Grade 2 who received treatment within ≤7 days of disease onset had the highest rate of complete recovery (32.9%, 23/70).
conclusionIn summary, using the physician decision support system, we successfully identified two predictors, the pretreatment hearing Grade 2 (26-45 dB) and treatment within ≤7 days of disease onset, associated with the highest odds of achieving complete recovery (<25 dB) of hearing in patients with ISSNHL.
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