Evidence map›Paper›PMID 33177247›Full record

ArticleAging2020

Prognostic risk signature based on the expression of three m6A RNA methylation regulatory genes in kidney renal papillary cell carcinoma.

Zhuolun Sun, Changying Jing, Chutian Xiao, Tengcheng Li, Yu Wang

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. RNA NNature reviews. Urology · 2024
    Review
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  7. Article
  8. Review
  9. Article
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  13. Multifaceted Roles of theBiomolecules · 2022
    Review
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  15. Article
  16. Essential mJournal of oncology · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zhuolun SunDepartment of Urology, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China.
Changying JingEye Institute of Shandong University of Traditional Chinese Medicine, Jinan 250002, China.
Chutian XiaoDepartment of Urology, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China.
Tengcheng LiDepartment of Urology, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China.
Yu WangDepartment of Urology, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China.
Sun Yat-sen University · CNShandong University of Traditional Chinese Medicine · CNThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the prognostic significance of the expression of N6-methyladenosine (m6A) RNA methylation regulatory genes in kidney renal papillary cell carcinoma (KIRP). RNA-sequencing data analysis showed that 14 of 20 major m6A RNA methylation regulatory genes were differentially expressed in the KIRP tissues from The Cancer Genome Atlas (TCGA) database. We constructed a prognostic risk signature with three m6A RNA methylation regulatory genes,

Indexed as

AdultAgedCarcinoma, Renal CellFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHeterogeneous-Nuclear Ribonucleoprotein Group CHumansKidney NeoplasmsMaleMethyltransferasesMiddle AgedPrognosisRisk FactorsRNA-Binding ProteinsRNA Processing, Post-TranscriptionalHeterogeneous-Nuclear Ribonucleoprotein Group CHNRNPC protein, humanIGF2BP3 protein, humanMethyltransferasesMETTL3 protein, humanRNA-Binding ProteinsVIRMA protein, humankidney renal papillary cell carcinomam6Aprognostic signatureRNA methylationsurvival analysis

Identifiers

PMID33177247
PMCPMC7695403
OpenAlexW3100443650

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.