Evidence map›Paper›PMID 33177161›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

TL1A-DR3 Plasma Levels Are Predictive of HIV-1 Disease Control, and DR3 Costimulation Boosts HIV-1-Specific T Cell Responses.

Bruna Oriol-Tordera, Alex Olvera, Clara Duran-Castells, Anuska Llano, Beatriz Mothe, Marta Massanella, Judith Dalmau, Carmela Ganoza, Jorge Sanchez, Maria Luz Calle and 7 more

Open access · bronzeAbstract readMulticenter StudyValidation Study
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Bruna Oriol-TorderaInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.ORCID 0000-0002-2714-9097
Alex OlveraInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.
Clara Duran-CastellsInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.ORCID 0000-0002-4034-5738
Anuska LlanoInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.
Beatriz MotheInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.
Marta MassanellaInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.ORCID 0000-0002-3326-151X
Judith DalmauInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.
Carmela GanozaAsociación Civil Impacta Salud y Educacion, Lima 15063, Peru.ORCID 0000-0001-6238-8504
Jorge SanchezAsociación Civil Impacta Salud y Educacion, Lima 15063, Peru.ORCID 0000-0001-6020-8266
Maria Luz CalleUniversitat de Vic - Universitat Central de Catalunya, Vic, 08500 Barcelona, Spain.ORCID 0000-0001-9334-415X
Bonaventura ClotetInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.
Javier Martinez-PicadoInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.ORCID 0000-0002-4916-2129
Eugènia NegredoUniversitat de Vic - Universitat Central de Catalunya, Vic, 08500 Barcelona, Spain.ORCID 0000-0001-5298-1734
Julià BlancoInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.
Dennis Hartigan-O'ConnorDepartment of Medical Microbiology and Immunology, University of California, Davis, Davis, CA 95616.
Christian BranderInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain.ORCID 0000-0002-0548-5778
Marta Ruiz-RiolInstitut de Recerca de la Sida IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Badalona, 08916 Barcelona, Spain; mruiz@irsicaixa.es.ORCID 0000-0003-1899-8879
Universitat de Vic - Universitat Central de Catalunya · ESIrsiCaixa · ESUniversitat Autònoma de Barcelona · ESUniversidad Peruana Cayetano Heredia · PEUniversity of California, San Francisco · USUniversity of Washington · US

Funding

UC Davis Biostatistics CoreP01AI131568 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HARTIGAN-O'CONNOR, DENNIS J. · 2017 to 2021
$7.1M
NIAID NIH HHS P01 AI131568
6 · The paper itself

Abstract

Relative control of HIV-1 infection has been linked to genetic and immune host factors. In this study, we analyzed 96 plasma proteome arrays from chronic untreated HIV-1-infected individuals using the classificatory random forest approach to discriminate between uncontrolled disease (plasma viral load [pVL] >50,000 RNA copies/ml; CD4 counts 283 cells/mm

Indexed as

AnimalsAntibodies, Monoclonal, Murine-DerivedCD4 Lymphocyte CountCD4-Positive T-LymphocytesFemaleHIV-1HIV InfectionsHumansMaleMiceReceptors, Tumor Necrosis Factor, Member 25Tumor Necrosis Factor Ligand Superfamily Member 15Antibodies, Monoclonal, Murine-DerivedReceptors, Tumor Necrosis Factor, Member 25TNFRSF25 protein, humanTNFSF15 protein, humanTumor Necrosis Factor Ligand Superfamily Member 15

Identifiers

PMID33177161
PMCPMC7725879
OpenAlexW3103344677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.