Evidence map›Paper›PMID 33177159›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Essential Role of Neutrophils in the Protective Immune Response Induced by a Live Attenuated

Parna Bhattacharya, Ranadhir Dey, Ankit Saxena, Subir Karmakar, Nevien Ismail, Sreenivas Gannavaram, Pradeep K Dagur, Monika Satoskar, Sanika Satoskar, Silvia De Paoli and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The History of Live AttenuatedPathogens (Basel, Switzerland) · 2022
    Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Parna BhattacharyaDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993; hira.nakhasi@fda.hhs.gov parna.bhattacharya@fda.hhs.gov.
Ranadhir DeyDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993.ORCID 0000-0003-0069-7867
Ankit SaxenaFlow Cytometry Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Subir KarmakarDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993.ORCID 0000-0002-6288-7335
Nevien IsmailDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993.ORCID 0000-0003-0294-8834
Sreenivas GannavaramDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993.ORCID 0000-0002-6557-8220
Pradeep K DagurFlow Cytometry Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Monika SatoskarNortheast Ohio Medical University, Rootstown, OH 44272.
Sanika SatoskarNortheast Ohio Medical University, Rootstown, OH 44272.
Silvia De PaoliOffice of Blood Research and Review, U.S. Food and Drug Administration, Silver Spring, MD 20993; and.
Kazuyo TakedaMicroscopy and Imaging Core Facility, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993.
John Philip McCoyFlow Cytometry Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-8118-5275
Hira L NakhasiDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD 20993; hira.nakhasi@fda.hhs.gov parna.bhattacharya@fda.hhs.gov.ORCID 0000-0003-4941-1620
Center for Biologics Evaluation and Research · USNational Institutes of Health · USNortheast Ohio Medical University · USUnited States Food and Drug Administration · US

Funding

Intramural FDA HHS FD999999
6 · The paper itself

Abstract

No licensed vaccine exists against visceral leishmaniasis (VL), a disease caused by the

Indexed as

Lymphocyte ActivationNeutrophil InfiltrationAnimalsFemaleLeishmania donovaniLeishmaniasis VaccinesLeishmaniasis, VisceralMiceNeutrophilsTh1 CellsVaccines, AttenuatedLeishmaniasis VaccinesVaccines, Attenuated

Identifiers

PMID33177159
PMCPMC7725841
OpenAlexW3105997678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.