Evidence map›Paper›PMID 33177141›Full record

ArticleBMJ open2020

Factors associated with attitudes towards HIV cure research among transgender women and travestis: a cross-sectional survey in São Paulo, Brazil.

Robert J Wozniak, Natalia B Cerqueira, Maria Candida S Dantas, Bianca Mahafe, Daniel A C Barros, Edmilson Alves de Medeiros, Ana Carolina Soares de Oliveira, Thiago Sabino, Albert Roggenbuck, Vivian Iida Avelino-Silva and 7 more

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Robert J WozniakDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA rjw4001@med.cornell.edu.ORCID 0000-0002-9990-1671
Natalia B CerqueiraDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Maria Candida S DantasDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Bianca MahafeDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Daniel A C BarrosDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Edmilson Alves de MedeirosDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Ana Carolina Soares de OliveiraDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Thiago SabinoDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Albert RoggenbuckDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Vivian Iida Avelino-SilvaDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Carrie D JohnstonDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Jez L MarstonDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Sebastian C BidegainDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.
Manya MagnusDepartment of Epidemiology, The George Washington University, Washington, District of Columbia, USA.
Esper G KallasDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.
Douglas F NixonDivision of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-2801-1786
Camila S DoniniDepartment of Infectious and Parasitic Diseases, University of Sao Paulo, São Paulo, São Paulo, Brazil.

Funding

SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral EradicationUM1AI126617 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI JONES, R. BRAD, NIXON, DOUGLAS F · 2016 to 2020
$28.1M
T32: Pathogenesis of Infectious Diseases Training ProgramT32AI007613 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ROY M. GULICK · 1999 to 2026
$8.8M
NIAID NIH HHS P30 AI117970NIAID NIH HHS T32 AI007613NIAID NIH HHS UM1 AI126617
6 · The paper itself

Abstract

objectiveCharacterising the perceptions of groups most affected by HIV is fundamental in establishing guidelines for biomedical advancement. Although Brazil has successfully fought HIV/AIDS through several measures, transgender women still have a likelihood of HIV infection 55 times higher than the general population. This study aimed to better understand the perception and awareness of HIV cure research among the trans-identifying population in São Paulo, Brazil, and to determine factors that motivate or discourage participation in HIV cure studies.

settingThis cross-sectional study analysed data collected from a questionnaire administered to 118 transgender women and travestis at 5 sites within the city of São Paulo. It uses quantitative methodology to describe the perspectives of transgender and travesti people in relation to HIV cure research and the context in which such perspectives are produced.

resultsOf 118 participants, most participants (73%) had some knowledge of HIV cure research and were most willing to participate in online surveys (52%), interviews (52%), focus groups (52%) and studies involving blood draws (57%). Those with a higher education or employment status were more likely to agree that someone had been cured of HIV, people living with HIV are discriminated against, and more information about HIV cure research is needed before the community embraces it. Only 55% of participants completely trusted their physician. The biggest motivational factors included gaining additional knowledge about HIV infection (77%) and the potential for a longer, healthier life for all (73%).

conclusionsAs a primary analysis of HIV cure attitudes among the transgender and travesti population as well as the social context in which they are formed, this study identifies opportunities to strengthen the dialogue and develop more educational collaborations between scientific investigators, community educators and the trans-identifying population to ensure that HIV cure research is inclusive of diverse perspectives.

Indexed as

HIV InfectionsTransgender PersonsAttitudeBrazilCross-Sectional StudiesFemaleHumansMaleepidemiologyhealth & safetyHIV & AIDSinternational health servicespublic healthquality in health care

Identifiers

PMID33177141
PMCPMC7661370

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.