ArticleScience advances2020
Expandable and implantable bioelectronic complex for analyzing and regulating real-time activity of the urinary bladder.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 78 citations in OpenAlex.
- A cross-shaped combined ultrasound array patch for continuous bladder volume monitoring.Photoacoustics · 2026Article
- Flexible ultrathin organic electrochemical transistor (OECT)-based portable system for monitoring and stimulation of bladder muscle.Flexible and printed electronics · 2026Article
- Real-Time Feedback Strategically Regulates Optoelectronics for Customized Optogenetic Spinal Cord Regeneration.Exploration (Beijing, China) · 2026Article
- Review of electroencephalography and electromyography research in robotics: opportunities and challenges.Visual computing for industry, biomedicine, and art · 2026Review
- Implantable soft bladder-machine interface for neurogenic bladder dysfunction.Nature communications · 2026Article
- Recent Technological Advances in Monitoring and Neuromodulation of Non-Malignant and Neurogenic Bladder Conditions.Advanced healthcare materials · 2026Review
- 4D printing of trigger-free shape-memory hydrogels towards self-adaptive substrates for bioelectronics.Nature communications · 2025Article
- Design of Soft, Stretchable Bladder-Integrated Scaffolds for Advanced Bioelectronic Implants.Advanced materials technologies · 2025Article
- A Hydro-Expansive and Degradable Biomaterial Enabling Shape Recovery of Film-Based Devices in Biofluids.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- A fully implantable sensorized artificial urinary bladder to restore continence and fullness monitoring.APL bioengineering · 2025Article
- Recent Advances in Stimuli-Responsive Materials and Soft Robotic Actuators for Bioelectronic Medicine.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Multifunctional bioelectronics for brain-body circuits.Nature reviews bioengineering · 2025Article
- Direct Stimulation of Gastric Smooth Muscle Cells via GNeurogastroenterology and motility · 2025Article
- Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems.Bioactive materials · 2025Review
- Human-Centric, Three Dimensional Micro Light-Emitting Diodes for Cosmetic and Medical Phototherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Emergent biotechnology applications in urology: a mini review.Frontiers in bioengineering and biotechnology · 2025Review
- A wireless, battery-free device for electrical neuromodulation of bladder contractions.Materials today. Bio · 2024Article
- Stretchable and biodegradable self-healing conductors for multifunctional electronics.Science advances · 2024Article
- Laser-driven hierarchical "gas-needles" for programmable and high-precision proximity transfer printing of microchips.Science advances · 2023Article
- Optical EUS Activation to Relax Sensitized Micturition Response.Life (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Underactive bladder or detrusor underactivity (DUA), that is, not being able to micturate, has received less attention with little research and remains unknown or limited on pathological causes and treatments as opposed to overactive bladder, although the syndrome may pose a risk of urinary infections or life-threatening kidney damage. Here, we present an integrated expandable electronic and optoelectronic complex that behaves as a single body with the elastic, time-dynamic urinary bladder with substantial volume changes up to ~300%. The system configuration of the electronics validated by the theoretical model allows conformal, seamless integration onto the urinary bladder without a glue or suture, enabling precise monitoring with various electrical components for real-time status and efficient optogenetic manipulation for urination at the desired time. In vivo experiments using diabetic DUA models demonstrate the possibility for practical uses of high-fidelity electronics in clinical trials associated with the bladder and other elastic organs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.