ArticleScience advances2020
Persistent epigenetic reprogramming of sweet taste by diet.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 51 citations in OpenAlex.
- Insulin receptor signaling in gustatory cells suppresses sugar taste sensitivity and feeding iniScience · 2026Article
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- Taste Preferences Shape Disease Susceptibility via Heritable Nutrient Predispositions: A Behavior-Gene Coevolution Framework.Genes, brain, and behavior · 2026Article
- EPOP restricts PRC2.1 targeting to chromatin by directly modulating enzyme complex dimerization.Nature communications · 2026Article
- A Profile of Flavourings in Commercial Complementary Foods in South Africa.Maternal & child nutrition · 2025Article
- New dimensions in the molecular genetics of insect chemoreception.Trends in genetics : TIG · 2025Review
- The impact of sugar diet on humidity preference, survival, and host landing in mosquitoes.Journal of medical entomology · 2025Article
- Taste Plasticity in Nutrition and Health: A Scoping Review.Nutrients · 2025Article
- Fat- and sugar-induced signals regulate sweet and fat taste perception in Drosophila.Cell reports · 2023Article
- Article
- NNature structural & molecular biology · 2023Article
- Polygenic adaptation to overnutrition reveals a role for cholinergic signaling in longevity.bioRxiv : the preprint server for biology · 2023Article
- Effects of hunger on neuronal histone modifications slow aging inScience (New York, N.Y.) · 2023Article
- Is Type 2 Diabetes Mellitus a Behavioural Disorder? An Evidence Review for Type 2 Diabetes Mellitus Prevention and Remission through Lifestyle Modification.TouchREVIEWS in endocrinology · 2023Review
- Health relevance of lowering postprandial glycaemia in the paediatric population through diet': results from a multistakeholder workshop.European journal of nutrition · 2023Review
- Nutrigenomic regulation of sensory plasticity.eLife · 2023Article
- High sucrose consumption decouples intrinsic and synaptic excitability of AgRP neurons without altering body weight.International journal of obesity (2005) · 2023Article
- Chemosensory Ability and Sensitivity in Health and Disease: Epigenetic Regulation and COVID-19.International journal of molecular sciences · 2023Review
- Food memory circuits regulate eating and energy balance.Current biology : CB · 2023Article
- Experience-dependent plasticity of gustatory insular cortex circuits and taste preferences.Science advances · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Diets rich in sugar, salt, and fat alter taste perception and food preference, contributing to obesity and metabolic disorders, but the molecular mechanisms through which this occurs are unknown. Here, we show that in response to a high sugar diet, the epigenetic regulator Polycomb Repressive Complex 2.1 (PRC2.1) persistently reprograms the sensory neurons of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.