ArticleCancer discovery2021
Lower Airway Dysbiosis Affects Lung Cancer Progression.
Open access · bronzeAbstract read
In one paragraph
Article in Cancer discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 211 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
211citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
211 citing papers in PubMed, 1 synthesis or guideline pooled it, 286 citations in OpenAlex.
- Meta-analysis of the human gut microbiome uncovers shared and distinct microbial signatures between diseases.mSystems · 2024Pooled it
- The role of the respiratory microbiome in acute and chronic respiratory diseases.Nature reviews. Microbiology · 2026Review
- Targeting the Tumor Microenvironment Network to Overcome Immunotherapy Resistance in Non-Small Cell Lung Cancer: Mechanisms to Clinical Translation.Cancer medicine · 2026Review
- Dynamic balance of the lung microbiome in health and respiratory diseases.Chinese medical journal · 2026Review
- Intra-tumoral microbiota: Key modulators of tumor immunity and therapeutic potential.Genes & diseases · 2026Review
- Bronchoalveolar lavage microbiota signatures and stage-associated alterations in early-stage and advanced-stage non-small cell lung cancer: a pilot study.Journal of translational medicine · 2026Article
- Microbial Influence on Immune Checkpoint Inhibitor Therapy in Non-Small Cell Carcinoma: The Gut-Lung-Immune Axis.Cancers · 2026Review
- Hallmarks of the ageing lung: 10 years later.The European respiratory journal · 2026Review
- Dynamic microbiome-host interactions and their associations with systemic metabolism and radiological characteristics during early lung adenocarcinoma.NPJ precision oncology · 2026Article
- Lower airway dysbiosis in nontuberculous mycobacteria-positive bronchiectasis is associated with neutrophil extracellular trap-predominant severe phenotypes.American journal of respiratory and critical care medicine · 2026Article
- The interaction between microbes and cytokines in cancer: unraveling the underlying effects.Journal of translational medicine · 2026Review
- 16S rRNA gene sequencing reveals distinct intratumoral bacterial microbiome signatures between CT indeterminate benign and early-stage malignant pulmonary lesions.Journal of translational medicine · 2026Article
- Integrative Analysis of Multiomic Pathways Predicts Cancer-Affected Lobes in Lung Cancer.Cancer prevention research (Philadelphia, Pa.) · 2026Article
- Valeric acid from oral microbiome suppresses esophageal cancer growth by disrupting eEF1A1 -mediated translational output.Nature communications · 2026Article
- A lung microbial signature for postoperative recurrence in stage I-II non-small cell lung cancer.Respiratory research · 2026Article
- The Dynamic Gut Microbiota: Monitoring Alterations During Lung Cancer Progression for Diagnosis and Precision Medicine.International journal of molecular sciences · 2026Review
- Curcumin as a Multi-Target Bioactive Molecule: Mechanistic Insights and Translational Perspectives.International journal of molecular sciences · 2026Review
- Review
- Microflora: a promising potential in the diagnosis and treatment of non-small cell lung cancer.International journal of clinical oncology · 2026Review
- Culturable and unculturable periodontal microorganisms in non-small cell lung cancer: an exploratory analysis.Scientific reports · 2026Article
151 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
42 authors at 7 institutions in 1 country.
Jun-Chieh J TsayDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Benjamin G WuDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Imran SulaimanDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Katherine GershnerSection of Pulmonary, Critical Care, Allergy and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Rosemary SchlugerDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Yonghua LiDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Ting-An YieDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Peter MeynNYU Langone Genomic Technology Center, New York University School of Medicine, New York, New York.
Evan OlsenDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Luisannay PerezDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Brendan FrancaDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Joseph CarpenitoDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Tadasu IizumiDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Mariam El-AshmawyDepartment of Medicine, New York University School of Medicine, New York, New York.
Michelle BadriDepartment of Biology, New York University, New York, New York.
James T MortonCenter for Computational Biology, Flatiron Institute, Simons Foundation, New York, New York.
Nan ShenDepartment of Genetics and Genomic Sciences and Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Linchen HeDepartment of Population Health, New York University School of Medicine, New York, New York.ORCID 0000-0001-6981-5492
Gaetane MichaudDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Samaan RafeqDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Jamie L BessichDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Robert L SmithDivision of Pulmonary and Critical Care Medicine, VA New York Harbor Healthcare System, New York, New York.
Harald SauthoffDivision of Pulmonary and Critical Care Medicine, VA New York Harbor Healthcare System, New York, New York.
Kevin FelnerDivision of Pulmonary and Critical Care Medicine, VA New York Harbor Healthcare System, New York, New York.
Ray PillaiDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.ORCID 0000-0002-8335-3463
Anastasia-Maria ZavitsanouDepartment of Pathology, New York University School of Medicine, New York, New York.
Sergei B KoralovDepartment of Pathology, New York University School of Medicine, New York, New York.ORCID 0000-0002-4843-3791
Valeria MezzanoDepartment of Pathology, New York University School of Medicine, New York, New York.
Cynthia A LoomisDepartment of Pathology, New York University School of Medicine, New York, New York.
Andre L MoreiraDepartment of Pathology, New York University School of Medicine, New York, New York.
William MooreDepartment of Radiology, New York University School of Medicine, New York, New York.
Aristotelis TsirigosDepartment of Pathology, New York University School of Medicine, New York, New York.ORCID 0000-0002-7512-8477
Adriana HeguyNYU Langone Genomic Technology Center, New York University School of Medicine, New York, New York.
William N RomDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.
Daniel H StermanDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York.ORCID 0000-0003-1249-0804
Harvey I PassDepartment of Cardiothoracic Surgery, New York University School of Medicine, New York, New York.
Jose C ClementeDepartment of Genetics and Genomic Sciences and Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Huilin LiDepartment of Population Health, New York University School of Medicine, New York, New York.
Richard BonneauDepartment of Biology, New York University, New York, New York.
Kwok-Kin WongDivision of Hematology and Oncology, New York University School of Medicine, New York, New York.
Thales PapagiannakopoulosDepartment of Pathology, New York University School of Medicine, New York, New York.
Leopoldo N SegalDivision of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, New York. Leopoldo.Segal@nyumc.org.ORCID 0000-0003-3559-9431
New York University · USVA NY Harbor Healthcare System · USIcahn School of Medicine at Mount Sinai · USNYU Langone Health · USSimons Foundation · USNew York Oncology Hematology · USWake Forest University · US
Funding
Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5MVaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Richard Lewis Possemato · 1985 to 2026
$83.1MInstitutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL, HOCHMAN, JUDITH S · 2012 to 2014
$16.8MNYU Lung Cancer Biomarker CenterU01CA086137 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ROM, WILLIAM N · 2000 to 2015
$15.3MLocal microbiota signatures of pro-tumor immunity and checkpoint inhibition susceptibility in lung cancerR37CA244775 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Leopoldo Nicolas Segal · 2020 to 2026
$4.7MTraining Program in Immunology and Inflammation.T32AI100853 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Susan Ruth Schwab · 2012 to 2026
$4.5MMicrobial triggers and molecular mechanisms of Th17 mediated airway inflammation-Resubmission-1R01HL125816 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KORALOV, SERGEI BORISOVICH · 2015 to 2019
$3.3MResearch Training for Physician-Scientists in Gastrointestinal OncologyT32CA193111 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BAR-SAGI, DAFNA, WOLFGANG, CHRISTOPHER L. · 2015 to 2024
$2.7MNovel Statistical Methods in Analyzing Microbiome Data for Longitudinal StudyR01DK110014 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LI, HUILIN · 2016 to 2019
$1.5MLung Microbiome and Inflammation in Early COPDK23AI102970 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGAL, LEOPOLDO NICOLAS · 2014 to 2017
$754kNCATS NIH HHS UL1 TR000038NCATS NIH HHS UL1 TR001445NCI NIH HHS P30 CA016087NCI NIH HHS R37 CA244775NCI NIH HHS T32 CA193111NCI NIH HHS U01 CA086137NHLBI NIH HHS R01 HL125816NIAID NIH HHS K23 AI102970NIAID NIH HHS T32 AI100853NIDDK NIH HHS R01 DK110014
Abstract
In lung cancer, enrichment of the lower airway microbiota with oral commensals commonly occurs, and
Indexed as
AdenocarcinomaAnimalsCohort StudiesDisease Models, AnimalDisease ProgressionDysbiosisFemaleHumansLung NeoplasmsMiceMice, TransgenicMicrobiotaNeoplasm MetastasisNeoplasm StagingNew YorkProportional Hazards Models
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.