ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2018
[Voxel-based analysis of cerebral blood flow changes in Parkinson disease using arterial spin labeling technique].
Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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9 authors at 1 institution in 1 country.
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Abstract
objectiveTo explore the imaging biomarker for early diagnosis and disease course monitoring of Parkinson disease (PD) in arterial spin labeling (ASL) technique.
methodsBetween July, 2014 and May, 2017, 23 patients with PD underwent magnetic resonance imaging (MRI) and ASL examinations in our hospital, including 13 in the early stage and 10 in advanced stages. Voxel-based analysis (VBA) was used to observe the regional cerebral blood flow (rCBF) characteristics in PD patients in different stages and three-dimensional continuous arterial spin labeling (3D CASL) was used to analyze the mean cerebral blood flow (mCBF).
resultsNo significant difference was found in mCBF among PD patients in the early stage, patients in advanced stages and normal control subjects (
conclusionsVBA of ASL reveals rCBF alterations in association with the disease progression in PD patients, suggesting that this technique might provide assistance in identification of potential markers for early PD diagnosis and for monitoring the disease course.
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