Evidence map›Paper›PMID 33176933›Full record

ArticleThe Science of the total environment2021

Detection of SARS-CoV-2 RNA in hospital wastewater from a low COVID-19 disease prevalence area.

José Gonçalves, Tom Koritnik, Verica Mioč, Marija Trkov, Maja Bolješič, Nataša Berginc, Katarina Prosenc, Tadeja Kotar, Metka Paragi

Open access · hybridAbstract read
In one paragraph

Article in The Science of the total environment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 118 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  11. Structured Ethical Review for Wastewater-Based Testing.medRxiv : the preprint server for health sciences · 2023
    Article
  12. Article
  13. Article
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  16. Strategies for safe management of hospital wastewater during the COVID-19 pandemic.International journal of environmental science and technology : IJEST · 2023
    Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

José GonçalvesDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia. Electronic address: zemcg5@gmail.com.
Tom KoritnikDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
Verica MiočDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
Marija TrkovDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
Maja BolješičDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
Nataša BergincDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
Katarina ProsencDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
Tadeja KotarDepartment of Infectious Diseases, University Medical Center, Ljubljana, Slovenia.
Metka ParagiDepartment for Public Health Microbiology, National Laboratory for Health, Environment and Food, Ljubljana, Slovenia.
National Laboratory of Health, Environment and Food · SILjubljana University Medical Centre · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies on SARS-CoV and MERS-CoV reported the detection of viral RNA in the stool of both symptomatic and asymptomatic individuals. These clinical observations suggest that municipal and hospital wastewater from affected communities may contain SARS-CoV-2 RNA. Recent studies have also reported the presence of SARS-CoV-2 RNA in human feces. Wastewater-based epidemiology (WBE) is a promising approach to understand the prevalence of viruses in a given catchment population, as wastewater contains viruses from symptomatic and asymptomatic individuals. The current study reports the first detection of SARS-CoV-2 RNA in untreated wastewater in Slovenia. Two sizes of centrifugal filters were tested: 30 kDa and 10 kDA AMICON® Ultra-15 Centrifugal Filters, where 10 kDA resulted in a higher concentration factor and higher recovery efficiency. The results in hospital wastewater show that WBE can be used for monitoring COVID -19 and could be applied in municipal wastewater treatment plants as a potential complementary tool for public health monitoring at population level.

Indexed as

COVID-19SARS-CoV-2HospitalsHumansPrevalenceRNASloveniaWastewaterRNAWastewaterCOVID-19qPCRSARS-CoV-2VirologyWastewaterWastewater-based epidemiology

Identifiers

PMID33176933
PMCPMC7591869
OpenAlexW3096963143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.