Evidence map›Paper›PMID 33176884›Full record

ReviewParasites & vectors2020

Human toxoplasmosis in Mozambique: gaps in knowledge and research opportunities.

Leonardo Manuel, Gabriela Santos-Gomes, Emilia V Noormahomed

Open access · goldAbstract readReview
In one paragraph

Review in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Seroprevalence and Risk Factors forResearch and reports in tropical medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Pan African medical journal · 2022
    Article
  11. Deep learning for microscopic examination of protozoan parasites.Computational and structural biotechnology journal · 2022
    Review
  12. Article
  13. Article
  14. Coinfection of HIV-1 withEC microbiology · 2021
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Leonardo ManuelFaculty of Health Sciences, Universidade Lurio, Nampula, Mozambique.
Gabriela Santos-GomesGlobal Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical (IHMT), Universidade Nova de Lisboa (UNL), Lisbon, Portugal.
Emilia V NoormahomedDepartment of Microbiology, Faculty of Medicine, Universidade Eduardo Mondlane (UEM), Maputo, Mozambique. enoormahomed@gmail.com.ORCID http://orcid.org/0000-0001-8874-1900
Eduardo Mondlane University · MZLúrio University · MZUniversidade Nova de Lisboa · PT

Funding

Enhancing Advanced Biomedical Training in MozambiqueD43TW010568 · FIC · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NOORMAHOMED, EMILIA VIRGINIA, SCHOOLEY, ROBERT TURNER · 2017 to 2021
$1.5M
FIC NIH HHS D43 TW010568FIC NIH HHS D43TW010568-02
6 · The paper itself

Abstract

Toxoplasmosis is a parasitic zoonotic disease caused by Toxoplasma gondii that afflicts humans worldwide and wild and domestic warm-blooded animals. In immunocompetent individuals, the acute phase of infection presents transient low or mild symptoms that remain unnoticed. In immunocompromised patients, T. gondii is a life-threatening opportunistic infection, which can result from the reactivation of latent infection or primary infection. Moreover, congenital toxoplasmosis, which results from the transplacental passage of tachyzoites into the fetus during a pregnant primary infection, can lead to miscarriage, stillbirth, or ocular and neurologic disease, and neurocognitive deficits in the newborns. Thus, the present review aims to address the current knowledge of T. gondii infection and toxoplasmosis in Africa and especially in Mozambique, stressing the importance of identifying risk factors and promote awareness among the health care providers and population, assessing the gaps in knowledge and define research priorities. In Mozambique, and in general in southern African countries, clinical disease and epidemiological data have not yet been entirely addressed in addition to the implications of T. gondii infection in immunocompetent individuals, in pregnant women, and its relation with neuropsychiatric disorders. The main gaps in knowledge in Mozambique include lack of awareness of the disease, lack of diagnostic methods in health facilities, lack of genetic data, and lack of control strategies.

Indexed as

AnimalsAntibodies, ProtozoanBiomedical ResearchFemaleHumansImmunocompromised HostImmunoglobulin GInfant, NewbornMozambiquePregnancyPregnancy Complications, ParasiticRisk FactorsToxoplasmaToxoplasmosisToxoplasmosis, CongenitalZoonosesAntibodies, ProtozoanImmunoglobulin GCongenital toxoplasmosisHIV-infected patientsMental disordersMozambiqueOcular toxoplasmosisSouth east African countriesToxoplasma gondii infection

Identifiers

PMID33176884
PMCPMC7659051
OpenAlexW3105318779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.