Evidence map›Paper›PMID 33176860›Full record

ArticleJournal of orthopaedic surgery and research2020

Clinical effects of staged joint replacement in patients with septic arthritic knee.

Ming Ni, Jun Fu, Tao Deng, Erlong Niu, Chi Xu, Xiang Li, Wei Chai, Guoqiang Zhang, Jiying Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ming NiThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Jun FuThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Tao DengThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Erlong NiuThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Chi XuThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Xiang LiThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Wei ChaiThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China.
Guoqiang ZhangThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. gqzhang301@163.com.
Jiying ChenThe First Medical Centre, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. jiyingchencn@126.com.
Chinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the clinical effect of staged joint replacement for the treatment of septic arthritic knee and the therapeutic differences between antibiotic cement beads and the tibial plateau spacer.

methodsTwenty-three patients (24 knee joints) treated with a staged joint replacement for septic arthritis knee were retrospectively reviewed between March 2014 and April 2018. At the first stage, thorough debridement and irrigation with self-made antibiotic cement beads or tibial plateau spacer were performed. After that, systemic antibiotic treatment was followed; when the infection was surely eliminated, the second-stage TKA was performed. Knee mobility (range of motion, abbreviated to ROM) and function (HSS scores system) were evaluated before surgery, in the interval period, and after joint replacement.

resultsAll patients finished follow-up, and the mean follow-up time was 27.3 months (12-54 months). Each group has one patient replaced with a homotypic spacer, and all patients eventually cleared the infection. None of the patients had a recurrent infection. The mobility and HSS scores of the two groups were significantly improved postoperation (p < 0.05). And there was no significant difference in the post-surgery ROM (p = 0.153) and the HSS score (p = 0.054) between the two groups.

conclusionStaged joint replacement is an efficacious way for septic arthritic knees, whether tibial plateau spacer or antibiotic cement beads were used, which can effectively control infection and improve knee function.

Indexed as

AgedAnti-Bacterial AgentsArthritis, InfectiousArthroplasty, Replacement, KneeBone CementsDebridementFemaleHumansKnee JointMaleMiddle AgedRange of Motion, ArticularTibiaTreatment OutcomeAnti-Bacterial AgentsBone CementsKneeSeptic arthritisSpacerTwo-staged joint replacement

Identifiers

PMID33176860
PMCPMC7661248
OpenAlexW3100821136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.