Evidence map›Paper›PMID 33176785›Full record

ArticleBMC health services research2020

Design of a care pathway for pharmacy-based PrEP delivery in Kenya: results from a collaborative stakeholder consultation.

Katrina F Ortblad, Peter Mogere, Stephanie Roche, Kevin Kamolloh, Josephine Odoyo, Elizabeth Irungu, Nelly R Mugo, Jillian Pintye, Jared M Baeten, Elizabeth Bukusi and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Katrina F OrtbladDepartment of Global Health, International Clinical Research Center, University of Washington, 908 Jefferson St, 12th floor, Seattle, WA, 98104, USA. katort@uw.edu.ORCID http://orcid.org/0000-0002-5675-8836
Peter MogerePartners in Health and Research Development, Thika, Kenya.
Stephanie RocheDepartment of Global Health, International Clinical Research Center, University of Washington, 908 Jefferson St, 12th floor, Seattle, WA, 98104, USA.
Kevin KamollohCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Josephine OdoyoCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Elizabeth IrunguDepartment of Global Health, International Clinical Research Center, University of Washington, 908 Jefferson St, 12th floor, Seattle, WA, 98104, USA.
Nelly R MugoPartners in Health and Research Development, Thika, Kenya.
Jillian PintyeDepartment of Global Health, International Clinical Research Center, University of Washington, 908 Jefferson St, 12th floor, Seattle, WA, 98104, USA.
Jared M BaetenDepartment of Global Health, International Clinical Research Center, University of Washington, 908 Jefferson St, 12th floor, Seattle, WA, 98104, USA.
Elizabeth BukusiDepartment of Global Health, International Clinical Research Center, University of Washington, 908 Jefferson St, 12th floor, Seattle, WA, 98104, USA.
Kenneth NgurePartners in Health and Research Development, Thika, Kenya.
Stakeholders for Pharmacy-based PrEP Delivery in Kenya Consultation
University of Washington · USHealth Alliance International · USJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Pharmacy delivery to expand the reach of PrEP in KenyaR34MH120106 · NIMH · UNIVERSITY OF WASHINGTON · PI ORTBLAD, KATRINA FRANCES · 2019 to 2020
$605k
Peer PrEP referral + HIV self-test for PrEP initiation among young Kenyan womenK99MH121166 · NIMH · UNIVERSITY OF WASHINGTON · PI ORTBLAD, KATRINA FRANCES · 2020 to 2020
$122k
NIAID NIH HHS P30 AI027757NIMH NIH HHS K99 MH121166NIMH NIH HHS R34 MH120106
6 · The paper itself

Abstract

introductionIn Kenya, pre-exposure prophylaxis (PrEP) for HIV prevention is almost exclusively delivered at HIV clinics. Developing novel PrEP delivery models is important for increasing the reach of PrEP. Delivery of PrEP through pharmacies is one approach utilized in the US to improve accessibility. Retail pharmacies are commonly used as a first-line access point for medical care in Kenya, but have not been utilized for PrEP delivery. We conducted a collaborative consultative meeting of stakeholders to develop a care pathway for pharmacy-based PrEP delivery in Kenya.

methodsIn January 2020, we held a one-day meeting in Nairobi with 36 stakeholders from PrEP regulatory, professional, healthcare service delivery, civil society, and research organizations. Attendees reviewed a theory of change model, results from formative qualitative research with pharmacy providers and clients, and anticipated core components of pharmacy-based PrEP delivery: counseling, HIV testing, prescribing, and dispensing. Stakeholders participated in small and large group discussions to identify potential challenges and solutions. We synthesized the key findings from these discussions.

resultsStakeholders were enthusiastic about a model for pharmacy-based PrEP delivery. Potential challenges identified included insufficient pharmacy provider knowledge and skills, regulatory hurdles to providing affordable HIV testing at pharmacies, and undefined pathways for PrEP procurement. Potential solutions identified included having pharmacy providers complete the Kenya Ministry of Health-approved PrEP training, use of a PrEP prescribing checklist with remote clinician oversight and provider-assisted HIV self-testing, and having the government provide PrEP and HIV self-testing kits to pharmacies during a pilot test. A care pathway was developed over the course of the meeting.

conclusionsPrEP delivery stakeholders in Kenya were strongly supportive of developing and testing a model for pharmacy-based PrEP delivery to increase PrEP access. We collaboratively developed a care pathway for pilot testing that has the potential to expand PrEP delivery options in Kenya and other similar settings.

Indexed as

Anti-HIV AgentsHIV InfectionsPharmaciesPharmacyPre-Exposure ProphylaxisHumansKenyaReferral and ConsultationAnti-HIV AgentsHIV preventionImplementation scienceKenyaPharmacy carePrEPStakeholders

Identifiers

PMID33176785
PMCPMC7661206
OpenAlexW3099534659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.