Evidence map›Paper›PMID 33176736›Full record

Observational studyBMC pregnancy and childbirth2020

Longitudinal change in arterial stiffness after delivery in women with preeclampsia and normotension: a prospective cohort study.

Sehun Kim, Hyun Ja Lim, Jeung-Ran Kim, Kyung Joon Oh, Joon-Seok Hong, Jung-Won Suh

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04142268 (Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic and Normotensive Women After Delivery), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04142268 completednot on this map

Comparison of Longitudinal Blood Pressure and Arterial Stiffness in Preeclamptic and Normotensive Women After Delivery: One-Year Follow-Up Results

Typeobservational_patient_registrySponsorSeoul National University HospitalRan2013 to 2017Enrolled73ConditionsPreeclampsia and Eclampsia, Stiffness, Aortic, Blood Pressure
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Preeclampsia Emerging as a Risk Factor of Cardiovascular Disease in Women.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sehun KimDepartment of Internal Medicine, Seongnam Citizens Hospital, Seongnam, Republic of Korea.
Hyun Ja LimDepartment of Community Health & Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Jeung-Ran KimDepartment of Internal Medicine, Cardiovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam, 13620, Republic of Korea.
Kyung Joon OhDepartment of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam, 13620, Republic of Korea.
Joon-Seok HongDepartment of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam, 13620, Republic of Korea. hjsobgy@gmail.com.
Jung-Won SuhDepartment of Internal Medicine, Cardiovascular Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam, 13620, Republic of Korea. dasome2@snu.ac.kr.ORCID http://orcid.org/0000-0002-0397-6071
Seoul National University Bundang Hospital · KRUniversity of Saskatchewan · CA

Funding

Seoul National Hospital 02-2013-077
6 · The paper itself

Abstract

backgroundPreeclampsia is associated with increased arterial stiffness during pregnancy. However, data on the longitudinal change in arterial stiffness after delivery in women with preeclampsia are lacking. In this pilot study, we aimed to examine the longitudinal change in arterial stiffness using the cardio-ankle vascular index after delivery in women with preeclamptic and normotensive pregnancies.

methodsWe enrolled pregnant women with preeclampsia (n = 37) and normotension (n = 36) who gave birth at Seoul National University Bundang Hospital between March 2013 and May 2016, and followed-up at day 1, 6 months, and 12 months after delivery. The longitudinal change in the cardio-ankle vascular index and other variables (blood pressure, lipid profiles, serum creatinine, and liver enzymes) were compared between the two groups using the mixed-effects model, and interactions among the main predictors were examined.

resultsThe longitudinal change in the cardio-ankle vascular index did not significantly differ between the two groups (β = 0.11, 95% CI: - 0.31-0.54, p = 0.60). Predictors of the longitudinal change in the cardio-ankle vascular index included age, time since delivery, body mass index, and diabetes mellitus. Women with preeclampsia showed significantly elevated blood pressure, lipid profiles, serum creatinine, and liver enzymes compared to women with normotension over the course of 1 year of follow-up.

conclusionsPreeclampsia is associated with unfavorable blood pressure and metabolic indices after delivery. However, we found no difference in the longitudinal change in arterial stiffness between women with preeclampsia and normotension over the course of 1 year after delivery.

trial registrationRetrospectively registered at ClinicalTrials.gov on October 29, 2019 ( NCT04142268 ).

Indexed as

Cardio Ankle Vascular IndexAdultBlood PressureCase-Control StudiesFemaleHumansPilot ProjectsPre-EclampsiaPregnancyProspective StudiesPulse Wave AnalysisRisk FactorsSeoulTime FactorsVascular StiffnessBlood pressureCardio-ankle vascular indexCardiovascular diseasesLongitudinal changePreeclampsiaPregnancyVascular stiffness

Identifiers

PMID33176736
PMCPMC7661192
OpenAlexW3103930318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.