Evidence map›Paper›PMID 33176650›Full record

ReviewCurrent neuropharmacology2021

Putative Involvement of Endocrine Disruptors in the Alzheimer's Disease Via the Insulin-Regulated Aminopeptidase/GLUT4 Pathway.

María Jesús Ramírez-Expósito, Jose Manuel Martínez-Martos, Vanesa Cantón-Habas, María Del Pilar Carrera-González

Open access · greenAbstract readReview
In one paragraph

Review in Current neuropharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Current updates on latest basic research of scientific relevance in hypertensive dementia.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

María Jesús Ramírez-ExpósitoDepartment of Health Sciences, Experimental and Clinical Physiopathology Research Group, Faculty of Experimental and Health Sciences, University of Jaen, E-23071 Jaen, Spain.
Jose Manuel Martínez-MartosDepartment of Health Sciences, Experimental and Clinical Physiopathology Research Group, Faculty of Experimental and Health Sciences, University of Jaen, E-23071 Jaen, Spain.
Vanesa Cantón-HabasDepartment of Nursing, Pharmacology and Physiotherapy, Faculty of Medicine and Nursing, Av. Menéndez Pidal, 7, 14004 Cordoba-Maimonides Institute of Biomedical Research of Cordoba (IMIBIC) IMIBIC Building, Reina Sofia University Hospital, Av. Menendez Pidal, s/n, 14004 Cordoba, Spain.
María Del Pilar Carrera-GonzálezDepartment of Health Sciences, Experimental and Clinical Physiopathology Research Group, Faculty of Experimental and Health Sciences, University of Jaen, E-23071 Jaen, Spain.
Universidad de Jaén · ESInstituto Maimónides de Investigación Biomédica de Córdoba · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been well established that there is a connection between type II diabetes (DMTII) and Alzheimer's disease (AD). In fact, the increase in AD incidence may be an emerging complication of DMTII. Both pathologies are related to estradiol (E

Indexed as

Alzheimer DiseaseDiabetes Mellitus, Type 2Endocrine DisruptorsAminopeptidasesCystinyl AminopeptidaseHumansInsulinAminopeptidasesCystinyl AminopeptidaseEndocrine DisruptorsInsulinAlzheimer's Diseasediabetesendocrine disruptorsestrogensglucose transporter 4.insulin-regulated aminopeptidase

Identifiers

PMID33176650
PMCPMC8686320
OpenAlexW3098604680

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.