Evidence map›Paper›PMID 33176616›Full record

ArticleUnited European gastroenterology journal2021

Time trends in incidence and prevalence of chronic pancreatitis: A 25-year population-based nationwide study.

Søren S Olesen, Laust H Mortensen, Elisabeth Zinck, Ulrik Becker, Asbjørn M Drewes, Camilla Nøjgaard, Srdan Novovic, Dhiraj Yadav, Janne S Tolstrup

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Idiopathic chronic pancreatitis: clinical highlights.Therapeutic advances in gastroenterology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. JGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  13. Article
  14. Chronic and Idiopathic Pancreatitis-A Personalized Treatment Approach.United European gastroenterology journal · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Søren S OlesenDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.ORCID 0000-0003-3916-3168
Laust H MortensenData Science Lab, Methods and Analysis, Statistics Denmark, Copenhagen, Denmark.
Elisabeth ZinckData Science Lab, Methods and Analysis, Statistics Denmark, Copenhagen, Denmark.
Ulrik BeckerNational Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Asbjørn M DrewesDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Camilla NøjgaardGastro Unit, Hvidovre University Hospital, Hvidovre, Denmark.
Srdan NovovicGastro Unit, Hvidovre University Hospital, Hvidovre, Denmark.
Dhiraj YadavDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Janne S TolstrupNational Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpdated population-based estimates on incidence and prevalence of chronic pancreatitis are scarce.

methodsWe used nationwide healthcare registries to identify all Danish patients diagnosed with chronic pancreatitis and computed crude and standardised incidence rates and prevalence estimates in 1994-2018. Incidence and prevalence were evaluated in relation to patients age and gender, aetiology (alcoholic vs. non-alcoholic) and smoking and alcohol consumption in the general Danish population.

resultsThe mean incidence rate of chronic pancreatitis during the study period was 12.6 per 100,000 person years for the total population, for women it was 8.6 per 100,000 person years and for men it was 16.7 per 100,000 person years. The standardised incidence rate was stable from 1994 to 2018, remaining at 12.5 per 100,000 person years in the last observation period (2014-2018). The point prevalence of chronic pancreatitis in 2016 was 153.9 per 100,000 persons. A gradual increase in standardised prevalence estimates was observed during the study period from 126.6 in 1996 to 153.9 in 2016. The mean age at chronic pancreatitis diagnosis increased from 52.1 to 60.0 years during the study period.

conclusionThe prevalence of chronic pancreatitis is increasing in the Danish population despite a stable incidence level. Improved management strategies and changes in the underlying patient population may explain these observations.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionAge of OnsetAlcohol DrinkingChildChild, PreschoolDenmarkFemaleHumansIncidenceInfantInfant, NewbornMalealcoholchronic pancreatitisepidemiologyincidenceprevalencesmoking

Identifiers

PMID33176616
PMCPMC8259237

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.