Evidence map›Paper›PMID 33176593›Full record

Trial reportPhlebology2021

A randomised controlled trial of neuromuscular stimulation in non-operative venous disease improves clinical and symptomatic status.

Raveena Ravikumar, Tristan Ra Lane, Adarsh Babber, Sarah Onida, Alun H Davies

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Phlebology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Raveena RavikumarSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK.
Tristan Ra LaneSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-8681-7075
Adarsh BabberSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK.
Sarah OnidaSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK.
Alun H DaviesSection of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, London, UK.ORCID https://orcid.org/0000-0001-5261-6913
Imperial College Healthcare NHS Trust · GBImperial College London · GBCambridge University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis randomised controlled trial investigates the dosing effect of neuromuscular electrical stimulation (NMES) in patients with chronic venous disease (CVD).

methodsSeventy-six patients with CEAP C3-C5 were randomised to Group A (no NMES), B (30 minutes of NMES daily) or C (60 minutes of NMES daily). Primary outcome was percentage change in Femoral Vein Time Averaged Mean Velocity (TAMV) at 6 weeks. Clinical severity scores, disease-specific and generic quality of life (QoL) were assessed.

resultsSeventy-six patients were recruited - mean age 60.8 (SD14.4) and 47:29 male. Six patients lost to follow-up. Percentage change in TAMV (p<0.001) was significantly increased in Groups B and C. Aberdeen Varicose Veins Questionnaire Score (-6.9, p=0.029) and Venous Clinical Severity Score (-4, p-0.003) improved in Group C, and worsened in Group A (+1, p=0.025).

conclusionsDaily NMES usage increases flow parameters, with twice daily usage improving QoL and clinical severity at 6 weeks in CVD patients.

Indexed as

Varicose VeinsVenous InsufficiencyChronic DiseaseFemoral VeinHumansMaleMiddle AgedQuality of LifeSeverity of Illness IndexSurveys and QuestionnairesTreatment OutcomeCEAP clinical classvenous diseasevenous refluxvenous severity scoreVenous stasis

Identifiers

PMID33176593
PMCPMC8044600
OpenAlexW3104777137

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.