Evidence map›Paper›PMID 33176581›Full record

ArticleTechnology in cancer research & treatment

LC3B in Malignant Cells Correlates With Immune Infiltrate in Hypopharyngeal Squamous Cell Carcinoma.

Sifan Gao, Jun Chen, Xiaowen Han, Dangjun Wei, Zhengsheng Wu, Chaobing Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sifan GaoDepartment of Otorhinolaryngology, Head and Neck Surgery, 36639The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.ORCID 0000-0002-1152-2790
Jun ChenDepartment of Otorhinolaryngology, Head and Neck Surgery, 36639The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Xiaowen HanDepartment of Pathology, 12485Anhui Medical University, Hefei, China.
Dangjun WeiDepartment of Otorhinolaryngology, Head and Neck Surgery, Taihe County Hospital of Traditional Chinese Medicine, Fuyang, Anhui, China.
Zhengsheng WuDepartment of Pathology, 12485Anhui Medical University, Hefei, China.
Chaobing GaoDepartment of Otorhinolaryngology, Head and Neck Surgery, 36639The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to investigate the between autophagy activity and local immune response in hypopharyngeal squamous cell carcinoma (HSCC). Herein, we observed the expression of autophagy marker microtubule-associated protein light chain 3B (MAP1LC3B), CD8 cytotoxic T lymphocytes (CTLs), CD39 (regulatory T cells Tregs) and CD163 (tumor-associated macrophages TAMs) in HSCC, and determined the prognostic roles of CD8

Indexed as

BiomarkersFemaleGene ExpressionHumansImmunohistochemistryImmunophenotypingKaplan-Meier EstimateLymphocytes, Tumor-InfiltratingMaleMicrotubule-Associated ProteinsNeoplasm MetastasisNeoplasm StagingPrognosisSquamous Cell Carcinoma of Head and NeckTumor-Associated MacrophagesBiomarkersMAP1LC3B protein, humanMicrotubule-Associated ProteinsautophagyCD163CD39CD8hypopharyngeal squamous cell carcinomaimmune cellLC3B

Identifiers

PMID33176581
PMCPMC7672751
OpenAlexW3102848777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.