Evidence map›Paper›PMID 33176542›Full record

ArticleJournal of feline medicine and surgery2021

Clinical reasoning in feline vestibular syndrome: which presenting features are the most important?

Nicholas J Grapes, Frances E Taylor-Brown, Holger A Volk, Steven De Decker

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Epileptic seizures in cats: practical approaches to diagnosis.Journal of feline medicine and surgery · 2026
    Review
  3. Article
  4. Feline atopic syndrome: An insight into its effects on the central nervous system through vestibular disease.The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nicholas J GrapesDepartment of Clinical Science and Services, Royal Veterinary College, North Mymms, Hatfield, UK.ORCID 0000-0002-8849-5508
Frances E Taylor-BrownNeurology and Neurosurgery, Cave Veterinary Specialists, West Buckland, Wellington, UK.
Holger A VolkDepartment of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany.
Steven De DeckerDepartment of Clinical Science and Services, Royal Veterinary College, North Mymms, Hatfield, UK.ORCID 0000-0002-2505-2152
Royal Veterinary College · GBUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to evaluate whether clinical variables from the history, clinical presentation, and physical and neurological examinations of cats with vestibular syndrome were statistically predictive of the underlying diagnosis.

methodsIn total, 174 cats presenting with vestibular syndrome between January 2010 and May 2019 were investigated. Univariate statistical analysis of clinical variables was performed and those statistically associated with a diagnosis were retained for multivariable binary logistic regression modelling.

resultsThe seven most prevalent diagnoses represented 95% of vestibular presentations, which included: otitis media/interna (n = 48), idiopathic vestibular syndrome (n = 39), intracranial neoplasia (n = 24), middle ear polyp (n = 17), feline infectious peritonitis (n = 13), thiamine deficiency (n = 13) and intracranial empyema (n = 11). Idiopathic vestibular syndrome was commonly associated with non-purebred cats and had 17.8 times the odds of an improving clinical progression (95% confidence interval [CI] 1.3-250.0; CONCLUSIONS AND RELEVANCE: Although it may be difficult to identify the underlying diagnosis in cats with vestibular syndrome from the presenting features alone, there are instances in which discrete clinical features may help to guide clinical reasoning when evaluating cats with vestibular presentations.

Indexed as

Cat DiseasesEmpyemaThiamine DeficiencyAnimalsCatsClinical ReasoningFemaleRetrospective Studiesclinical reasoninghead tiltHorner syndromeneurologyotitis media/internaVestibular syndrome

Identifiers

PMID33176542
PMCPMC10812200
OpenAlexW3104525642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.