Evidence map›Paper›PMID 33176423›Full record

ArticleACS infectious diseases2021

Mucin-Degrading Microbes Release Monosaccharides That Chemoattract

Melinda A Engevik, Amy C Engevik, Kristen A Engevik, Jennifer M Auchtung, Alexandra L Chang-Graham, Wenly Ruan, Ruth Ann Luna, Joseph M Hyser, Jennifer K Spinler, James Versalovic

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
1.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Measuring C. difficile Adhesion to Mucosal Surfaces.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  7. Article
  8. Gut microbes · 2025
    Article
  9. Review
  10. Dissecting the role of flagellar subunits inJournal of bacteriology · 2025
    Article
  11. Gut microbes · 2025
    Article
  12. Sugar Import SuppressesbioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Unravelling three-way interactions betweenJournal of medical microbiology · 2025
    Review
  15. The Biology ofAnnual review of microbiology · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Melinda A EngevikDepartment of Pathology & Immunology, Baylor College of Medicine Houston Texas 77030, United States.ORCID 0000-0002-9742-9932
Amy C EngevikDepartment of Surgery, Vanderbilt University School of Medicine, Nashville Tennessee 37232, United States.
Kristen A EngevikDepartment of Molecular Virology and Microbiology, Baylor College of Medicine Houston Texas 77030, United States.ORCID 0000-0001-9807-1875
Jennifer M AuchtungDepartment of Molecular Virology and Microbiology, Baylor College of Medicine Houston Texas 77030, United States.
Alexandra L Chang-GrahamDepartment of Molecular Virology and Microbiology, Baylor College of Medicine Houston Texas 77030, United States.
Wenly RuanDepartment of Pathology & Immunology, Baylor College of Medicine Houston Texas 77030, United States.
Ruth Ann LunaDepartment of Pathology & Immunology, Baylor College of Medicine Houston Texas 77030, United States.
Joseph M HyserDepartment of Molecular Virology and Microbiology, Baylor College of Medicine Houston Texas 77030, United States.
Jennifer K SpinlerDepartment of Pathology & Immunology, Baylor College of Medicine Houston Texas 77030, United States.
James VersalovicDepartment of Pathology & Immunology, Baylor College of Medicine Houston Texas 77030, United States.
Baylor College of Medicine · USUniversity of Nebraska–Lincoln · USVanderbilt University · US

Funding

Proteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI STEPHEN A DUNCAN · 2020 to 2026
$8.8M
Research Training in Pediatrics GastroenterolgyT32DK007664 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI DOUGLAS G BURRIN · 1991 to 2026
$8.4M
The role of Myosin Vb in Hepatocyte Protein TraffickingK01DK121869 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ENGEVIK, AMY C · 2019 to 2023
$669k
Identifying the role of serotonin receptor 4 and trefoil factor 3 in intestinal wound repairK01DK123195 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ENGEVIK, MELINDA ANNE · 2020 to 2024
$612k
Regulation of secretory diarrhea by ER-PM junction signalingF30DK112563 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI CHANG-GRAHAM, ALEXANDRA · 2017 to 2019
$128k
NIDDK NIH HHS F30 DK112563NIDDK NIH HHS K01 DK121869NIDDK NIH HHS K01 DK123195NIDDK NIH HHS P30 DK123704NIDDK NIH HHS T32 DK007664
6 · The paper itself

Abstract

It is widely accepted that the pathogen

Indexed as

ClostridioidesClostridioides difficileEubacterialesHumansMonosaccharidesMucinsMucusMonosaccharidesMucinsAkkermansiaBacteroidesClostridioides difficileglycansMUC2Rumminococcus

Identifiers

PMID33176423
PMCPMC8110611
OpenAlexW3101477057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.