Evidence map›Paper›PMID 33176392›Full record

Trial reportActa obstetricia et gynecologica Scandinavica2021

Dosage of oxytocin for augmentation of labor and women's childbirth experiences: A randomized controlled trial.

Lotta Selin, Marie Berg, Ulla-Britt Wennerholm, Anna Dencker

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Acta obstetricia et gynecologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01587625 (High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01587625 nacompletednot on this map

High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour

TypeinterventionalSponsorGöteborg UniversityRan2013 to 2016Enrolled1,376ConditionsBirth, DelayedArmsOxytocin
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Oxytocin in Women's Health and Disease.Frontiers in endocrinology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lotta SelinInstitute of Health and Care Sciences, Sahlgrenska Academy, Gothenburg, Sweden.ORCID 0000-0001-9553-1274
Marie BergInstitute of Health and Care Sciences, Sahlgrenska Academy, Gothenburg, Sweden.
Ulla-Britt WennerholmDepartment of Obstetrics and Gynecology, Region Vastra Gotaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
Anna DenckerInstitute of Health and Care Sciences, Sahlgrenska Academy, Gothenburg, Sweden.
Sahlgrenska University Hospital · SERegion Västra Götaland · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to compare childbirth experiences and experience of labor pain in primiparous women who had received high- vs low-dose oxytocin for augmentation of delayed labor. MATERIAL AND

methodsA multicenter, parallel, double-blind randomized controlled trial took place in six Swedish labor wards. Inclusion criteria were healthy primiparous women at term with uncomplicated singleton pregnancies, cephalic fetal presentation, spontaneous onset of labor, confirmed delayed labor progress and ruptured membranes. The randomized controlled trial compared high- vs low-dose oxytocin used for augmentation of a delayed labor progress. The Childbirth Experience Questionnaire version 2 (CEQ2) was sent to the women 1 month after birth. The CEQ2 consists of 22 items in four domains: Own capacity, Perceived safety, Professional support and Participation. In addition, labor pain was reported with a visual analog scale (VAS) 2 hours postpartum and 1 month after birth. The main outcome was the childbirth experience measured with the four domains of the CEQ2. The clinical trial number is NCT01587625.

resultsThe CEQ2 was sent to 1203 women, and a total of 1008 women (83.8%) answered the questionnaire. The four domains of childbirth experience were scored similarly in the high- and low-dose oxytocin groups of women: Own capacity (P = .36), Perceived safety (P = .44), Professional support (P = .84), Participation (P = .49). VAS scores of labor pain were reported as similar in both oxytocin dosage groups. Labor pain was scored higher 1 month after birth compared with 2 hours postpartum. There was an association between childbirth experiences and mode of birth in both the high- and low-dose oxytocin groups.

conclusionsDifferent dosage of oxytocin for augmentation of delayed labor did not affect women's childbirth experiences assessed through CEQ2 1 month after birth, or pain assessment 2 hours or 1 month after birth.

Indexed as

OxytocicsAdultDouble-Blind MethodFemaleHumansLabor, ObstetricLabor PainOxytocinPain MeasurementPain PerceptionParturitionPatient ParticipationPatient SafetyPregnancySurveys and QuestionnairesSwedenOxytocicsOxytocinbirthchildbirth experiencedelayed laborlabor painoxytocin augmentationrandomized controlled trial

Identifiers

PMID33176392
PMCPMC8248083
OpenAlexW3101960059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.