Evidence map›Paper›PMID 33176023›Full record

ArticleClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology2021

Patterns and trends in eczema management in UK primary care (2009-2018): A population-based cohort study.

Simon de Lusignan, Helen Alexander, Conor Broderick, John Dennis, Andrew McGovern, Clarie Feeney, Carsten Flohr

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Atopic eczema in primary care: evidence update and implications for practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
  7. Article
  8. Article
  9. Care pathways in atopic dermatitis: a retrospective population-based cohort study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Patterns and trends in eczema management in UK primary care (2009-2018): A population-based cohort study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Simon de LusignanNuffield Department of Primary Care health Sciences, University of Oxford, Oxford, UK.
Helen AlexanderUnit for Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust and King's College London, London, UK.
Conor BroderickUnit for Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust and King's College London, London, UK.
John DennisMomentum Data, Pendragon House, St. Albans, UK.
Andrew McGovernMomentum Data, Pendragon House, St. Albans, UK.
Clarie FeeneyPfizer Ltd, Tadworth, UK.
Carsten FlohrUnit for Population-Based Dermatology Research, St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust and King's College London, London, UK.ORCID 0000-0003-4884-6286
King's College London · GBMomentum (United Kingdom) · GBPfizer (United Kingdom) · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the high disease burden of eczema, a contemporary overview of the patterns and trends in primary care healthcare utilization and treatment is lacking.

objectiveTo quantify primary care consultations, specialist referrals, prescribing, and treatment escalation, in children and adults with eczema in England.

methodsA large primary care research database was used to examine healthcare and treatment utilization in people with active eczema (n = 411,931). Management trends and variations by age, sex, socioeconomic status, and ethnicity were described from 2009 to 2018 inclusive.

resultsPrimary care consultation rates increased from 87.8 (95% confidence interval [95% CI] 87.3-88.3) to 112.0 (95% CI 111.5-112.6) per 100 person-years over 2009 to 2018. Specialist referral rates also increased from 3.8 (95% CI 3.7-3.9) to 5.0 (95% CI 4.9-5.1) per 100 person-years over the same period. Consultation rates were highest in infants. Specialist referrals were greatest in the over 50s and lowest in people of lower socioeconomic status, despite a higher rate of primary care consultations. There were small changes in prescribing over time; emollients increased (prescribed to 48.5% of people with active eczema in 2009 compared to 51.4% in 2018) and topical corticosteroids decreased (57.3%-52.0%). Prescribing disparities were observed, including less prescribing of potent and very potent topical corticosteroids in non-white ethnicities and people of lower socioeconomic status. Treatment escalation was more common with increasing age and in children of non-white ethnicity. CONCLUSION AND CLINICAL RELEVANCE: The management of eczema varies by sociodemographic status in England, with lower rates of specialist referral in people from more-deprived backgrounds. There are different patterns of healthcare utilization, treatment, and treatment escalation in people of non-white ethnicity and of more-deprived backgrounds.

Indexed as

Social ClassAdministration, CutaneousAdministration, OralAdolescentAdultAge FactorsAnti-Infective AgentsChildChild, PreschoolDermatitis, AtopicEmollientsEthnicityFemaleGlucocorticoidsHealthcare DisparitiesHistamine AntagonistsAnti-Infective AgentsEmollientsGlucocorticoidsHistamine AntagonistsImmunomodulating Agentsatopic dermatitisatopic eczemadermatologyeczemaepidemiologyprimary caretreatment

Identifiers

PMID33176023
PMCPMC7984383
OpenAlexW3105880737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.