ArticlePLoS genetics2020
Selection of GmSWEET39 for oil and protein improvement in soybean.
Article in PLoS genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.
- Pooled it
- Genome-Wide Identification of theInternational journal of molecular sciences · 2026Article
- Loss-of-function allele of the soybean flowering/maturation gene TOF11 increases free amino acid content at the edamame stage and improves eating quality.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Cell wall invertase improves grain nutrition via regulating sugar and hormone metabolism gene expression in transgenic soybean.Annals of botany · 2026Article
- Characterization ofFrontiers in plant science · 2026Article
- Metabolic engineering of soybean for improving grain quality for animal consumption.Frontiers in plant science · 2026Review
- Targets and strategies to design soybean seed composition traits.The plant genome · 2025Review
- A natural allele ofProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dissecting seed composition QTL from wild soybean: fine-mapping, candidate gene identification, and evaluation of introgression effects on agronomic performance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- GmSop20 Functions as a Key Coordinator of the Oil-To-Protein Ratio in Soybean Seeds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Deciphering the role of monoacylglycerol lipases (MAGL) under abiotic stress and lipid metabolism in soybean (Glycine max L.).Plant biotechnology journal · 2025Article
- Functional Genomics: From Soybean to Legume.International journal of molecular sciences · 2025Review
- Article
- AlphaFold-Guided Bespoke Gene Editing Enhances Field-Grown Soybean Oil Contents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Dissecting the genetic architecture of polygenic nutritional traits in maize through meta-QTL analysis.Food chemistry. Molecular sciences · 2025Article
- Loss of phytochromobilin synthase activity leads to larger seeds with higher protein content in soybean.BMC plant biology · 2025Article
- Integration of GWAS and transcriptome and haplotype analyses to identify QTNs and candidate genes controlling oil content in soybean seeds.Scientific reports · 2025Article
- Soybean genome‑wide association study of seed weight, protein, and oil content in the southeastern USA.Molecular genetics and genomics : MGG · 2025Article
- A genome-wide association study prioritizes VRN1-2 as a candidate gene associated with plant height in soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Characterization of a G. max × G. soja nested association mapping population and identification of loci controlling seed composition traits from wild soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soybean [Glycine max (L.) Merr.] was domesticated from wild soybean (G. soja Sieb. and Zucc.) and has been further improved as a dual-use seed crop to provide highly valuable oil and protein for food, feed, and industrial applications. However, the underlying genetic and molecular basis remains less understood. Having combined high-confidence bi-parental linkage mapping with high-resolution association analysis based on 631 whole sequenced genomes, we mapped major soybean protein and oil QTLs on chromosome15 to a sugar transporter gene (GmSWEET39). A two-nucleotide CC deletion truncating C-terminus of GmSWEET39 was strongly associated with high seed oil and low seed protein, suggesting its pleiotropic effect on protein and oil content. GmSWEET39 was predominantly expressed in parenchyma and integument of the seed coat, and likely regulates oil and protein accumulation by affecting sugar delivery from maternal seed coat to the filial embryo. We demonstrated that GmSWEET39 has a dual function for both oil and protein improvement and undergoes two different paths of artificial selection. A CC deletion (CC-) haplotype H1 has been intensively selected during domestication and extensively used in soybean improvement worldwide. H1 is fixed in North American soybean cultivars. The protein-favored (CC+) haplotype H3 still undergoes ongoing selection, reflecting its sustainable role for soybean protein improvement. The comprehensive knowledge on the molecular basis underlying the major QTL and GmSWEET39 haplotypes associated with soybean improvement would be valuable to design new strategies for soybean seed quality improvement using molecular breeding and biotechnological approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.