Evidence map›Paper›PMID 33175531›Full record

ArticleJournal of the American Chemical Society2020

Uncoupling the Folding-Function Paradigm of Lytic Peptides to Deliver Impermeable Inhibitors of Intracellular Protein-Protein Interactions.

Stephen E Miller, Kohei Tsuji, Rachel P M Abrams, Terrence R Burke, Joel P Schneider

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. CpACpP:ACS omega · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephen E MillerChemical Biology Laboratory, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 United States.ORCID 0000-0002-6988-2465
Kohei TsujiChemical Biology Laboratory, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 United States.ORCID 0000-0003-4773-8793
Rachel P M AbramsSection of Infections of the Nervous System, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda Maryland 20892, United States.
Terrence R BurkeChemical Biology Laboratory, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 United States.ORCID 0000-0001-9925-8586
Joel P SchneiderChemical Biology Laboratory, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702 United States.ORCID 0000-0002-4403-7900

Funding

Design and Utility of Novel Protienaceous BiomaterialsZIABC011313 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SCHNEIDER, JOEL · 2010 to 2025
$19.0M
Intramural NIH HHS ZIA BC011313
6 · The paper itself

Abstract

Here, we describe the use of peptide backbone

Indexed as

Amino Acid SequenceCell Cycle CheckpointsCell Cycle ProteinsCell Line, TumorCell MembraneCell SurvivalDrug CarriersHumansMicroscopy, ConfocalPeptidesPolo-Like Kinase 1Protein FoldingProtein Interaction Domains and MotifsProtein Kinase InhibitorsProtein Serine-Threonine KinasesProtein Structure, SecondaryCell Cycle ProteinsDrug CarriersPeptidesPolo-Like Kinase 1Protein Kinase InhibitorsProtein Serine-Threonine KinasesProto-Oncogene Proteins

Identifiers

PMID33175531
PMCPMC8916162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.