Evidence map›Paper›PMID 33175506›Full record

ArticleJournal of agricultural and food chemistry2020

Proanthocyanidin Block Arrays (PACBAR) for Comprehensive Capture and Delineation of Proanthocyanidin Structures.

Shuxi Jing, Wayne E Zeller, Daneel Ferreira, Bin Zhou, Joo-Won Nam, Ana Bedran-Russo, Shao-Nong Chen, Guido F Pauli

Open access · greenAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Journal of natural products · 2022
    Review
  9. B-type Proanthocyanidins with Dentin Biomodification Activity from Cocoa (Journal of agricultural and food chemistry · 2022
    Article
  10. Article
  11. Proanthocyanidin Tetramers and Pentamers fromJournal of natural products · 2022
    Article
  12. Unveiling structure-activity relationships of proanthocyanidins with dentin collagen.Dental materials : official publication of the Academy of Dental Materials · 2021
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Shuxi JingPharmacognosy Institute and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Wayne E ZellerUnited States Dairy Forage Research Center, Agricultural Research Service (ARS), United States Department of Agriculture (USDA), Madison, Wisconsin 53706, United States.ORCID http://orcid.org/0000-0002-1883-4519
Daneel FerreiraNational Center for Natural Products Research and Department of Biomolecular Sciences, Division of Pharmacognosy, School of Pharmacy, University of Mississippi, University, Mississippi 38677, United States.ORCID http://orcid.org/0000-0002-9375-7920
Bin ZhouState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, People's Republic of China.
Joo-Won NamCollege of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do 38541, Republic of Korea.ORCID http://orcid.org/0000-0001-5502-0736
Ana Bedran-RussoDepartment of General Dental Sciences, School of Dentistry, Marquette University, Milwaukee, Wisconsin 53233, United States.ORCID http://orcid.org/0000-0002-3670-9519
Shao-Nong ChenPharmacognosy Institute and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID http://orcid.org/0000-0003-0748-0863
Guido F PauliPharmacognosy Institute and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID http://orcid.org/0000-0003-1022-4326
University of Illinois Chicago · USAgricultural Research Service · USChinese Academy of Sciences · CNMarquette University · USUniversity of Mississippi · USYeungnam University · KR

Funding

Dentin Biomodification for Optimization of Bioadhesive Dental RestorationsR01DE028194 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2019 to 2023
$2.6M
Biomodification of Dentin Matrix StructureR01DE021040 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2011 to 2015
$2.1M
Biomodification of Dentin Matrix StructureR56DE021040 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2017 to 2017
$648k
NIDCR NIH HHS R01 DE021040NIDCR NIH HHS R01 DE028194NIDCR NIH HHS R56 DE021040
6 · The paper itself

Abstract

Proanthocyanidins (PACs) are near-ubiquitous and chemically complex metabolites, prototypical of higher plants. Their roles in food/feed/nutrition and ethnomedicine are widely recognized but poorly understood. With the analysis of evidence that underlies this challenge, this perspective identifies shortcomings in capturing and delineating PAC structures as key factors. While several groups have forwarded new representations, a consensus method that captures PAC structures concisely and offers high integrity for electronic storage is required to reduce confusion in this expansive field. The PAC block arrays (PACBAR) system fills this gap by providing precise and human- and machine-readable structural descriptors that capture PAC metabolomic structural diversity. PACBAR enables communication of PAC structures for the development of precise structure-activity relationships and will assist in advancing PAC research to the next level.

Indexed as

ProanthocyanidinsFruitHumansPlant ExtractsPlant ExtractsProanthocyanidinsnomenclaturepolyphenolsproanthocyanidinsstructure−activity relationships

Identifiers

PMID33175506
PMCPMC8010997
OpenAlexW3101363418

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.