Observational studyEuropean journal of neurology2021
The Unruptured Intracranial Aneurysm Treatment Score as a predictor of aneurysm growth or rupture.
Observational study in European journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic association between the lncRNA ANRIL rs10757272 polymorphism and intracranial aneurysm susceptibility in Asians.Neurosurgical review · 2022Pooled it
- Radiomics and deep learning for intracranial aneurysm rupture-status assessment on CTA/MRA: a multicenter retrospective study.Frontiers in neuroscience · 2026Article
- Serum Desmosine Levels Might Be Associated with the Size of Ruptured Cerebral Aneurysms in Patients with Aneurysmal Subarachnoid Hemorrhage-A Preliminary Study.Journal of clinical medicine · 2025Article
- Retrospective Application of Risk Scores to Unruptured Anterior Communicating Artery Aneurysms.Journal of clinical medicine · 2024Article
- Enhancing intracranial aneurysm rupture risk prediction with a novel multivariable logistic regression model incorporating high-resolution vessel wall imaging.Frontiers in neurology · 2024Article
- Clinical Scales in Aneurysm Rupture Prediction.Stroke (Hoboken, N.J.) · 2024Review
- A Future Blood Test to Detect Cerebral Aneurysms.Cellular and molecular neurobiology · 2023Review
- Geometric uncertainty in intracranial aneurysm rupture status discrimination: a two-site retrospective study.BMJ open · 2022Article
- Current decision support tools fail to agree or predict therapeutic decisions in a single cohort of unruptured intracranial aneurysms.Acta neurochirurgica · 2022Article
- Risk factors of intracranial infection in patients after intracranial aneurysm surgery: Implication for treatment strategies.Medicine · 2021Article
- Application of unruptured aneurysm scoring systems to a cohort of ruptured aneurysms: are we underestimating rupture risk?Neurosurgical review · 2021Article
- VICTORIA: VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms.Cardiovascular engineering and technology · 2021Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeThe Unruptured Intracranial Aneurysm Treatment Score (UIATS) was built to harmonize the treatment decision making on unruptured intracranial aneurysms. Therefore, it may also function as a predictor of aneurysm progression. In this study, we aimed to assess the validity of the UIATS model to identify aneurysms at risk of growth or rupture during follow-up.
methodsWe calculated the UIATS for a consecutive series of conservatively treated unruptured intracranial aneurysms, included in our prospectively kept neurovascular database. Computed tomography angiography and/or magnetic resonance angiography imaging at baseline and during follow-up was analyzed to detect aneurysm growth. We defined rupture as a cerebrospinal fluid or computed tomography-proven subarachnoid hemorrhage. We calculated the area under the receiver operator curve, sensitivity, and specificity, to determine the performance of the UIATS model.
resultsWe included 214 consecutive patients with 277 unruptured intracranial aneurysms. Aneurysms were followed for a median period of 1.3 years (range 0.3-11.7 years). During follow-up, 17 aneurysms enlarged (6.1%), and two aneurysms ruptured (0.7%). The UIATS model showed a sensitivity of 80% and a specificity of 44%. The area under the receiver operator curve was 0.62 (95% confidence interval 0.46-0.79).
conclusionsOur observational study involving consecutive patients with an unruptured intracranial aneurysm showed poor performance of the UIATS model to predict aneurysm growth or rupture during follow-up.
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