Evidence map›Paper›PMID 33175207›Full record

SynthesisRheumatology international2021

The global prevalence of rheumatoid arthritis: a meta-analysis based on a systematic review.

Khalid Almutairi, Johannes Nossent, David Preen, Helen Keen, Charles Inderjeeth

4 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Rheumatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 352 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
352citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05671497 phase2 / phase3completednot on this mapstarted 2022, after this paper: background citation

Evaluation of the Effect of Cilostazol on the Clinical Outcomes of Rheumatoid Arthritis Patients

TypeinterventionalSponsorAin Shams UniversityRan2022 to 2024Enrolled70ConditionsRheumatoid ArthritisArmsCilostazol 100 MG, conventional synthetic antirheumatic drugs
NCT06295848 nacompletednot on this mapstarted 2022, after this paper: background citation

The Effects of 6-week Cardiac Rehabilitation Programme on Cardiovascular Disease Risk, Systolic and Diastolic Blood Pressure and Disease Activity in Hypertensive Rheumatoid Arthritis Patients : A Randomised Controlled Trial

TypeinterventionalSponsorKayseri City HospitalRan2022 to 2024Enrolled40ConditionsCardiac Rehabilitation, Rheumatoid Arthritis, HypertensionArmsExercise
NCT06915701 phase2 / phase3recruitingnot on this mapstarted 2026, after this paper: background citation

"Evaluation of the Effect of Vitamin E (α-tocopherol) Supplementation on Clinical Activity and Inflammation in Patients With Rheumatoid Arthritis"

TypeinterventionalSponsorUniversity of GuadalajaraRan2026 to 2027Enrolled46ConditionsRheumatoid ArthritisArmsWill take vitamin E 800mg/day, Will take 200mg/day magnesium oxide placebo.
NCT07388407 recruitingnot on this mapstarted 2024, after this paper: background citation

Pharmacogenetics of Leflunomide in the RA Management

Typeobservational_patient_registrySponsorFoundation University IslamabadRan2024 to 2026Enrolled110ConditionsRhematoid ArthritisArmsStudy for the correlation of SNPs with efficacy and toxicity of Leflunomide in RA patients
3 · Its place in the literature

Who cites it

352 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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292 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khalid AlmutairiSchool of Medicine, The University of Western Australia, Perth, Australia. khalid.almutairi@research.uwa.edu.au.ORCID 0000-0002-9246-7294
Johannes NossentSchool of Medicine, The University of Western Australia, Perth, Australia.ORCID 0000-0002-2833-7997
David PreenSchool of Population and Global Health, Faculty of Health and Medical Sciences, University of Western Australia, Perth, WA, Australia.ORCID 0000-0002-2982-2169
Helen KeenSchool of Medicine, The University of Western Australia, Perth, Australia.ORCID 0000-0002-8469-2424
Charles InderjeethSchool of Medicine, The University of Western Australia, Perth, Australia.ORCID 0000-0003-0535-963X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective is to determine the global population prevalence of rheumatoid arthritis (RA) based on population-based studies and assess factors that influence RA prevalence estimates. Four electronic databases were searched (ProQuest Central, MEDLINE, Web of Science, and EMBASE) for peer-reviewed English publications that report prevalence estimates of RA from 1980 and 2019. We included case-control studies, cross-sectional studies, and prospective or retrospective cohort studies in our search strategy. A random-effect meta-analysis model was used to produce the pooled prevalence estimates. The potential between-study heterogeneity was identified using sensitivity analysis, sub-group and meta-regression analyses. A total of 67 studies were included in the meta-analysis, containing 742,246 RA patients and 211,592,925 healthy controls in the study period. The global RA prevalence estimate was 0.46% (95% confidence interval [CI] 0.39-0.54; I

Indexed as

Arthritis, RheumatoidCase-Control StudiesGlobal HealthHumansPrevalenceRegression AnalysisArthritisEpidemiologyMeta-analysisPrevalenceRheumatoid

Identifiers

PMID33175207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.