Evidence map›Paper›PMID 33175124›Full record

ReviewJAMA dermatology2021

Consensus Statement for the Management and Treatment of Port-Wine Birthmarks in Sturge-Weber Syndrome.

Sara Sabeti, Karen L Ball, Craig Burkhart, Lawrence Eichenfield, Esteban Fernandez Faith, Ilona J Frieden, Roy Geronemus, Deepti Gupta, Andrew C Krakowski, Moise L Levy and 4 more

Abstract readReviewConsensus Statement
In one paragraph

Review in JAMA dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Laser and light-based treatments for port-wine birthmarks - a systematic review and network meta-analysis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Ophthalmic screening in phakomatoses.Frontiers in cell and developmental biology · 2026
    Article
  9. Article
  10. Racial Differences in Work Relative Value Units for Outpatient Pediatric Dermatology Visits.JID innovations : skin science from molecules to population health · 2025
    Article
  11. A rare case report of Sturge-Weber syndrome type 2 variant on Roach scale.Journal of family medicine and primary care · 2025
    Article
  12. Article
  13. A diagnostic approach to neurocutaneous syndromes.Arquivos de neuro-psiquiatria · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. EndothelialFrontiers in cell and developmental biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sara SabetiDepartment of Dermatology, University of California, Irvine School of Medicine, Irvine.
Karen L BallThe Sturge-Weber Foundation, Houston, Texas.
Craig BurkhartDepartment of Dermatology, University of North Carolina, Chapel Hill.
Lawrence EichenfieldDepartment of Pediatric and Adolescent Dermatology, University of California, San Diego.
Esteban Fernandez FaithDivision of Dermatology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio.
Ilona J FriedenDepartment of Dermatology, School of Medicine, University of California, San Francisco.
Roy GeronemusDepartment of Dermatology, New York University School of Medicine, New York.
Deepti GuptaDepartment of Pediatrics, Division of Dermatology, Seattle Children's Hospital/University of Washington School of Medicine, Seattle.
Andrew C KrakowskiDepartment of Dermatology, St Luke's University Health Network, Easton, Pennsylvania.
Moise L LevyPediatric and Adolescent Dermatology, Dell Children's Medical Center, Austin, Texas.
Denise MetryDepartment of Dermatology, Baylor College of Medicine, Houston, Texas.
J Stuart NelsonDepartment of Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine.
Megha M TollefsonDepartment of Dermatology and Pediatrics, Mayo Clinic, Rochester, Minnesota.
Kristen M KellyDepartment of Dermatology, University of California, Irvine School of Medicine, Irvine.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NCATS NIH HHS UL1 TR001414
6 · The paper itself

Abstract

Importance: Sturge-Weber syndrome (SWS) is a neurocutaneous syndrome involving the skin, brain, and eyes. Consensus recommendations for management are lacking. Objective: To consolidate the current literature with expert opinion to make recommendations that will guide treatment and referral for patients with port-wine birthmarks (PWBs). Evidence Review: In this consensus statement, 12 nationally peer-recognized experts in dermatology with experience treating patients with SWS were assembled. Key topics and questions were formulated for each group and included risk stratification, optimum treatment strategies, and recommendations regarding light-based therapies. A systematic PubMed search was performed of English-language articles published between December 1, 2008, and December 1, 2018, as well as other pertinent studies identified by the expert panel. Clinical practice guidelines were recommended. Findings: Treatment of PWBs is indicated to minimize the psychosocial impact and diminish nodularity and potentially tissue hypertrophy. Better outcomes may be attained if treatments are started at an earlier age. In the US, pulsed dye laser is the standard for all PWBs regardless of the lesion size, location, or color. When performed by experienced physicians, laser treatment can be safe for patients of all ages. The choice of using general anesthesia in young patients is a complex decision that must be considered on a case-by-case basis. Conclusions and Relevance: These recommendations are intended to help guide clinical practice and decision-making for patients with SWS and those with isolated PWBs and may improve patient outcomes.

Indexed as

ConsensusClinical Decision-MakingDermatologyHumansLasers, DyeLow-Level Light TherapyPort-Wine StainPractice Guidelines as TopicSturge-Weber SyndromeTreatment Outcome

Identifiers

PMID33175124
PMCPMC8547264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.