ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2021
Genome sequence of Hydrangea macrophylla and its application in analysis of the double flower phenotype.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 28 citations in OpenAlex.
- A highly contiguous genome assembly of Cyclamen persicum to accelerate functional genomics and breeding.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026Article
- Decoding the complete mitochondrial genome of Hydrangea chinensis maxim.: insights into genomic recombination, gene transfer, and RNA editing dynamics.BMC plant biology · 2025Article
- Genome assembly of Stewartia sinensis reveals origin and evolution of orphan genes in Theaceae.Communications biology · 2025Article
- TheHorticulture research · 2025Article
- Repeatome landscapes and cytogenetics of hortensias provide a framework to trace Hydrangea evolution and domestication.Annals of botany · 2025Article
- Two haplotype-resolved genomes reveal important flower traits in bigleaf hydrangea (Horticulture research · 2023Article
- Recent Advances in Assembly of Complex Plant Genomes.Genomics, proteomics & bioinformatics · 2023Review
- Haplotype resolved chromosome level genome assembly ofHorticulture research · 2023Article
- Diversity analyses in two ornamental and large-genomeFrontiers in plant science · 2023Article
- Recurrent symmetrical bendings cause dwarfing inFrontiers in plant science · 2023Article
- The Current Developments in Medicinal Plant Genomics Enabled the Diversification of Secondary Metabolites' Biosynthesis.International journal of molecular sciences · 2022Review
- Exploring the Molecular Mechanism of Sepal Formation in the Decorative Flowers ofInternational journal of molecular sciences · 2022Article
- De novo phasing resolves haplotype sequences in complex plant genomes.Plant biotechnology journal · 2022Review
- The complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2021Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to its high ornamental value, the double flower phenotype of hydrangea (Hydrangea macrophylla) is one of its most important traits. In this study, genome sequence information was obtained to explore effective DNA markers and the causative genes for double flower production in hydrangea. Single-molecule real-time sequencing data followed by a Hi-C analysis were employed. Two haplotype-phased sequences were obtained from the heterozygous genome of hydrangea. One assembly consisted of 3,779 scaffolds (2.256 Gb in length and N50 of 1.5 Mb), the other also contained 3,779 scaffolds (2.227 Gb in length, and N50 of 1.4 Mb). A total of 36,930 genes were predicted in the sequences, of which 32,205 and 32,222 were found in each haplotype. A pair of 18 pseudomolecules was constructed along with a high-density single-nucleotide polymorphism (SNP) genetic linkage map. Using the genome sequence data, and two F2 populations, the SNPs linked to double flower loci (djo and dsu) were discovered. DNA markers linked to djo and dsu were developed, and these could distinguish the recessive double flower allele for each locus, respectively. The LEAFY gene is a very likely candidate as the causative gene for dsu, since frameshift was specifically observed in the double flower accession with dsu.
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