Evidence map›Paper›PMID 33175004›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2020

RELATIONS BETWEEN ASTHMA AND OBESITY: AN ANALYSIS OF MULTIPLE FACTORS.

Leticia Nabuco de Oliveira Madeira, Maria Alice Neves Bordallo, Marcos Antonio Borges, Agnaldo José Lopes, Isabel Rey Madeira, Fábio Chigres Kuschnir

Open access · diamondAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. COVID-19 and Pediatric Asthma: Clinical and Management Challenges.International journal of environmental research and public health · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leticia Nabuco de Oliveira MadeiraUniversidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0003-1004-1335
Maria Alice Neves BordalloUniversidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0002-3901-1087
Marcos Antonio BorgesUniversidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0002-7347-9441
Agnaldo José LopesUniversidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0001-8598-4878
Isabel Rey MadeiraUniversidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0001-5819-3915
Fábio Chigres KuschnirUniversidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID http://orcid.org/0000-0003-1432-2396
Universidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAsthma and obesity are prevalent and interrelated diseases. In the pediatric population, the effect of systemic inflammation associated to obesity, leading to inflammation of the airways, is currently controversial. Our aim was to compare inflammatory, clinical and spirometric patterns between children with asthma and obesity and those within the normal weight status range.

methodsA total of 79 boys and girls from 6 to 10 years old were selected and divided into four groups: obese asthmatics, non-obese asthmatics, obese non-asthmatics, and non-obese non-asthmatics. In addition to collecting clinical and anthropometric data, all children underwent spirometry and skin prick tests for inhalant allergens. Blood samples for measurement of cytokines and adipokines were also collected.

resultsObese asthmatics had significantly worse control of asthma than non-obese asthmatics (OR 4.9; 95%CI 1.1‒22.1), regardless of sex, physical activity and atopy. No differences in spirometry, Th1 and Th2 cytokines and adipokines levels were observed among the four groups. The prick tests were positive in 81.8 and 80% of non-obese asthmatics and obese asthmatics, respectively.

conclusionsThe degree of control of asthma was significantly lower in the obese group, regardless of the findings of no differences in spirometry. Extra-pulmonary factors could be responsible for this symptomatic profile. High positivity of skin test in both groups, which is considered a good marker of atopy, shows a preponderant atopic component in the genesis of asthma, both in children with obesity and in those within the normal weight status.

Indexed as

Adrenal Cortex HormonesAsthmaBrazilChildCross-Sectional StudiesFemaleHumansMalePediatric ObesitySeverity of Illness IndexSpirometrySurveys and QuestionnairesAdrenal Cortex Hormones

Identifiers

PMID33175004
PMCPMC7649860
OpenAlexW3095766143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.