Evidence map›Paper›PMID 33174843›Full record

ArticleeLife2020

Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells.

Lorena Benedetti, Jonathan S Marvin, Hanieh Falahati, Andres Guillén-Samander, Loren L Looger, Pietro De Camilli

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 72 citations in OpenAlex.

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  17. Synthetic Lipid Biology.Chemical reviews · 2025
    Review
  18. Article
  19. Selective optogenetic inhibition of GαProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lorena BenedettiDepartment of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, United States.ORCID 0000-0003-3510-0258
Jonathan S MarvinHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, United States.
Hanieh FalahatiDepartment of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, United States.
Andres Guillén-SamanderDepartment of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, United States.
Loren L LoogerHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, United States.ORCID 0000-0002-7531-1757
Pietro De CamilliDepartment of Neuroscience and Cell Biology, Yale University School of Medicine, New Haven, United States.ORCID 0000-0001-9045-0723
Howard Hughes Medical Institute · US

Funding

Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Richard A Flavell · 1993 to 2026
$44.0M
Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI Marina R Picciotto · 2004 to 2026
$37.1M
MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGR01NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 1997 to 2021
$4.7M
Molecular Mechanisms in Synaptic Vesicle RecyclingR37NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 2010 to 2016
$2.7M
Howard Hughes Medical InstituteNIDA NIH HHS P30 DA018343NIDDK NIH HHS P30 DK045735NIH HHS DA018343NIH HHS NS36251NINDS NIH HHS R01 NS036251NINDS NIH HHS R37 NS036251
6 · The paper itself

Abstract

Light-inducible dimerization protein modules enable precise temporal and spatial control of biological processes in non-invasive fashion. Among them, Magnets are small modules engineered from the

Indexed as

Biological TransportLightOptogeneticsProtein EngineeringAnimalsChlorocebus aethiopsCOS CellsDimerizationFungal ProteinsHeLa CellsHumansKineticsLipid MetabolismMice, Inbred C57BLOrganellesPhosphatidylinositol PhosphatesFungal Proteinsphosphatidylinositol 4-phosphatePhosphatidylinositol PhosphatesVVD protein, Neurospora crassacell biologycontact siteshumanlight-dependent dimerizersLOV domainorganelle contactsVAPVivid

Identifiers

PMID33174843
PMCPMC7735757
OpenAlexW3102082362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.