ArticleNucleic acids research2021
OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more.
Article in Nucleic acids research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 2 of them syntheses that pooled it.
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Who cites it
132 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- OMAMO: orthology-based alternative model organism selection.Bioinformatics (Oxford, England) · 2022Pooled it
- The Brachypodium distachyon cold-acclimated plasma membrane proteome is primed for stress resistance.G3 (Bethesda, Md.) · 2021Pooled it
- Intersecting experimental evolution and CRISPR screens to identify novel toxin resistance loci.eLife · 2026Article
- A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity.Nature communications · 2026Article
- A single-cell transcriptomic atlas reveals the emergence of medusa-specific cell states in the scyphozoan Aurelia coerulea.PLoS biology · 2026Article
- Discovering New Orthologous Groups with P-COGs.Biochemical genetics · 2026Article
- The developing leaf of the wild grass Brachypodium distachyon at single-cell resolution.The Plant cell · 2026Article
- Proximity proteomics reveals a co-evolved LRRK2-regulatory network linked to centrosomes.EMBO reports · 2026Article
- ProteomeLM: A proteome-scale language model enables accurate and rapid prediction of protein-protein interactions and gene essentiality across taxa.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Gene regulatory co-option drives birdsong neural circuit specialization.bioRxiv : the preprint server for biology · 2026Article
- Article
- Evolution of intrinsically disordered regions in vertebrate galectins for phase separation.EMBO reports · 2026Article
- An Equatorial Hemispheric Barrier Shapes the Diversification of Migratory Belenois Butterflies.Molecular ecology · 2026Article
- Splicing regulation and intron evolution in the short-intron ciliate model of endosymbiosis Paramecium bursaria.Nucleic acids research · 2026Article
- OmniPath: integrated knowledgebase for multi-omics analysis.Nucleic acids research · 2026Article
- OMAnnotator: a novel approach to building an annotated consensus genome sequence.Bioinformatics advances · 2026Article
- Reconstructing Evolutionary Histories with Hierarchical Orthologous Groups.Journal of molecular evolution · 2025Review
- Multi-omics-based insights into tomato adaptation to multifactorial stress combination.Plant physiology · 2025Article
- Pleiotropy increases with gene age in six model multicellular eukaryotes.Evolution letters · 2025Article
- Annotation matters: the effect of structural gene annotation on orthology inference.Bioinformatics (Oxford, England) · 2025Article
72 more citing papers are in PubMed but not listed here.
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12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
OMA is an established resource to elucidate evolutionary relationships among genes from currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise orthologs, functional annotations, local and global gene order conservation (synteny) information, among many other functions. This update paper describes the reorganisation of the database into gene-, group- and genome-centric pages. Other new and improved features are detailed, such as reporting of the evolutionarily best conserved isoforms of alternatively spliced genes, the inferred local order of ancestral genes, phylogenetic profiling, better cross-references, fast genome mapping, semantic data sharing via RDF, as well as a special coronavirus OMA with 119 viruses from the Nidovirales order, including SARS-CoV-2, the agent of the COVID-19 pandemic. We conclude with improvements to the documentation of the resource through primers, tutorials and short videos. OMA is accessible at https://omabrowser.org.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.