Evidence map›Paper›PMID 33174493›Full record

ArticleJournal of neurophysiology2021

Cellular interactions between social experience, alcohol sensitivity, and GABAergic inhibition in a crayfish neural circuit.

Lucy S Venuti, Norma L Pena-Flores, Jens Herberholz

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Lucy S VenutiNeuroscience and Cognitive Science Program.
Norma L Pena-FloresDepartment of Psychology, University of Maryland, College Park, Maryland.
Jens HerberholzNeuroscience and Cognitive Science Program.ORCID 0000-0001-7584-5903
Institute for Cognitive Science Studies · IRUniversity of Maryland, College Park · US

Funding

Modulation of Alcohol Effects on Nervous System Function by Social ExperienceR03AA025213 · NIAAA · UNIV OF MARYLAND, COLLEGE PARK · PI HERBERHOLZ, JENS · 2017 to 2018
$152k
NIAAA NIH HHS R03 AA025213
6 · The paper itself

Abstract

We report here that prior social experience modified the behavioral responses of adult crayfish to acute alcohol exposure. Animals housed individually for 1 wk before alcohol exposure were less sensitive to the intoxicating effects of alcohol than animals housed in groups, and these differences are based on changes in the nervous system rather than differences in alcohol uptake. To elucidate the underlying neural mechanisms, we investigated the neurophysiological responses of the lateral giant (LG) interneurons after alcohol exposure. Specifically, we measured the interactions between alcohol and different GABA

Indexed as

Social BehaviorSynaptic PotentialsAnimalsAstacoideaEthanolGABA AgonistsGABA-A Receptor AntagonistsGABAergic NeuronsInterneuronsIsoxazolesPhosphinic AcidsPyridines(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acidEthanolGABA AgonistsGABA-A Receptor AntagonistsgaboxadolIsoxazolesPhosphinic AcidsPyridinesalcoholcrayfishinhibitionneuronssocial

Identifiers

PMID33174493
PMCPMC8087379
OpenAlexW3105393687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.