Evidence map›Paper›PMID 33174453›Full record

ReviewAmerican journal of physiology. Gastrointestinal and liver physiology2021

Gut bioengineering strategies for regenerative medicine.

John D O'Neill, Meghan R Pinezich, Brandon A Guenthart, Gordana Vunjak-Novakovic

Abstract readReview
In one paragraph

Review in American journal of physiology. Gastrointestinal and liver physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Gut-on-a-chip for disease models.Journal of tissue engineering
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John D O'NeillDepartment of Biomedical Engineering, Columbia University, New York, New York.
Meghan R PinezichDepartment of Biomedical Engineering, Columbia University, New York, New York.
Brandon A GuenthartDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California.ORCID 0000-0002-9864-0035
Gordana Vunjak-NovakovicDepartment of Biomedical Engineering, Columbia University, New York, New York.

Funding

Tissue Engineering Resource Center: TTDP41EB027062 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Gordana Vunjak-Novakovic · 2019 to 2026
$12.6M
Multi-tissue platform for modeling systemic pathologiesUH3EB025765 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VUNJAK-NOVAKOVIC, GORDANA · 2019 to 2021
$4.0M
Multi-tissue platform for modeling systemic pathologiesUG3EB025765 · NIBIB · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VUNJAK-NOVAKOVIC, GORDANA · 2017 to 2019
$2.8M
Limited Competition for the Continuation of the Intestinal Stem Cell Consortium Coordinating CenterU24DK085532 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2019 to 2023
$2.3M
NIBIB NIH HHS P41 EB027062NIBIB NIH HHS UG3 EB025765NIBIB NIH HHS UH3 EB025765NIDDK NIH HHS U24 DK085532NIH HHS EB027062
6 · The paper itself

Abstract

Gastrointestinal disease burden continues to rise in the United States and worldwide. The development of bioengineering strategies to model gut injury or disease and to reestablish functional gut tissue could expand therapeutic options and improve clinical outcomes. Current approaches leverage a rapidly evolving gut bioengineering toolkit aimed at

Indexed as

Regenerative MedicineAnimalsBioengineeringGastrointestinal MicrobiomeHumansOrganoidsRegenerationStem Cellsbioengineeringbiomaterialscell therapygastrointestinal diseasemicrophysiological systemsorganoidsorgan-on-chipregenerative medicinestem cellstissue engineering

Identifiers

PMID33174453
PMCPMC8112187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.