Evidence map›Paper›PMID 33174390›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Conformational Modulation of Iduronic Acid-Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound and Implications for Development of Antimetastatic Platinum Drugs.

Anil K Gorle, Thomas Haselhorst, Samantha J Katner, Arun V Everest-Dass, James D Hampton, Erica J Peterson, Jennifer E Koblinski, Eriko Katsuta, Kazuaki Takabe, Mark von Itzstein and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Amphiphilic Glycoprobes for Cell Surface Engineering and Drug Delivery.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. On the Biology of Werner's Complex.Angewandte Chemie (International ed. in English) · 2021
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Anil K GorleInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, 4222, Australia.ORCID 0000-0001-7838-2625
Thomas HaselhorstInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, 4222, Australia.ORCID 0000-0002-3373-8680
Samantha J KatnerDepartment of Chemistry, Virginia Commonwealth University, Richmond, VA, 23284-2006, USA.
Arun V Everest-DassInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, 4222, Australia.ORCID 0000-0002-3795-0291
James D HamptonDepartment of Chemistry, Virginia Commonwealth University, Richmond, VA, 23284-2006, USA.
Erica J PetersonDepartment of Chemistry, Virginia Commonwealth University, Richmond, VA, 23284-2006, USA.
Jennifer E KoblinskiMassey Cancer Center, Virginia Commonwealth University, Richmond, VA, 23298-0037, USA.ORCID 0000-0002-7156-2030
Eriko KatsutaDepartment of Surgical Oncology, Roswell Park Comprehensive Cancer Center, University at Buffalo, Buffalo, NY, 14203, USA.
Kazuaki TakabeDepartment of Surgical Oncology, Roswell Park Comprehensive Cancer Center, University at Buffalo, Buffalo, NY, 14203, USA.
Mark von ItzsteinInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, 4222, Australia.ORCID 0000-0001-6302-7524
Susan J Berners-PriceInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, 4222, Australia.ORCID 0000-0002-7129-0039
Nicholas P FarrellInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, Queensland, 4222, Australia.ORCID 0000-0001-7160-7182
Griffith University · AUVirginia Commonwealth University · USRoswell Park Comprehensive Cancer Center · USMinnesota State University, Mankato · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
Sphingosine-1 Phosphate in Breast Cancer Progression and LymphangiogenesisR01CA160688 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI TAKABE, KAZUAKI · 2012 to 2016
$1.5M
NCI NIH HHS P30 CA016059NCI NIH HHS R01 CA160688
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsCell Line, TumorCell MovementDensity Functional TheoryGlycosaminoglycansHeparan SulfateHumansIduronic AcidMagnetic Resonance SpectroscopyMolecular ConformationOrganoplatinum CompoundsPlatinumAntineoplastic AgentsGlycosaminoglycansHeparan SulfateIduronic AcidOrganoplatinum CompoundsPlatinumtriplatinNCanticanceranti-metastaticcomputational chemistryglycosaminoglycansheparan sulfate

Identifiers

PMID33174390
PMCPMC7902481
OpenAlexW3105334529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.