ArticleHippocampus2021
The effect of body mass index on hippocampal morphology and memory performance in late childhood and adolescence.
Article in Hippocampus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- High-Resolution Diffusion Kurtosis Imaging of Hippocampus Subfields Across the Healthy Lifespan.NMR in biomedicine · 2026Article
- Memory Performance in Adolescents Living With Obesity: Brain Activation During Encoding and Retrieval in a Case-Control Study.Obesity science & practice · 2026Article
- Adolescents Who Are Overweight or Obese Exhibit Weaker Spatial and Verbal Working Memory Compared with Healthy-Weight Peers.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- Sex Differences in the Association Between Body Composition and Cognitive Performance in Adolescents With Type 1 Diabetes.Diabetes/metabolism research and reviews · 2026Observational
- Is there a role for higher cognitive processes in the development of obesity in humans?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Influence of exclusive breastfeeding on hippocampal structure, satiety responsiveness, and weight status.Maternal & child nutrition · 2022Article
- Retrieval-induced forgetting in children and adolescents with and without obesity.International journal of obesity (2005) · 2022Article
- Higher body mass index is associated with worse hippocampal vasoreactivity to carbon dioxide.Frontiers in aging neuroscience · 2022Article
- Memory and eating: A bidirectional relationship implicated in obesity.Neuroscience and biobehavioral reviews · 2022Review
- Selective morphological and volumetric alterations in the hippocampus of children exposed in utero to gestational diabetes mellitus.Human brain mapping · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Childhood obesity is associated with negative physiological and cognitive health outcomes. The hippocampus is a diverse subcortical structure involved in learned feeding behaviors and energy regulation, and research has shown that the hippocampus is vulnerable to the effects of excess adiposity. Previous studies have demonstrated reduced hippocampal volume in overweight and obese children; however, it is unclear if certain subregions are selectively affected. The purpose of this study was to determine how excess body weight influences regional hippocampal surface morphology and memory performance in a large cross-sectional cohort of 588 children and adolescents between 8.33 and 19.92 years of age using body mass index expressed as a percentage of the 95th percentile cutoff (%BMIp95). We demonstrate %BMIp95 is associated with reduced radial thickness in the superior anterior region of the left hippocampus, and this relationship is predominantly driven by children younger than 14 years. We also found %BMIp95 was associated with worse performance on a spatial episodic memory task and this relationship was partially mediated by the radial thickness of the significant shape cluster. These results demonstrate the differential influence of excess body weight on regional hippocampal structure and hippocampal-dependent behavior in children and adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.