SynthesisInternal and emergency medicine2021
Gender differences and survival after an out-of-hospital cardiac arrest: a systematic review and meta-analysis.
Synthesis in Internal and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 48 citations in OpenAlex.
- Sex-based differences in clinical outcomes among cardiogenic shock patients treated with mechanical circulatory support.Journal of thrombosis and thrombolysis · 2026Article
- Equal cardiac arrest care - a qualitative study of healthcare professionals' experiences.BMC medical ethics · 2026Article
- Article
- Association Between the Duration of Elevated Perfusion Pressure and Neurological Outcomes in Out-of-Hospital Cardiac Arrest Survivors.Reviews in cardiovascular medicine · 2025Article
- Diversity of CPR manikins for basic life support education: use of manikin sex, race and body shape - a scoping review.Emergency medicine journal : EMJ · 2025Article
- Sex Differences in In-Hospital Mortality Among Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation and Extracorporeal Cardiopulmonary Resuscitation: A Propensity Score-Matched Analysis.Journal of the American Heart Association · 2025Article
- Sex disparities in ICU care and outcomes after cardiac arrest: a Swiss nationwide analysis.Critical care (London, England) · 2025Article
- Sex differences and gender-oriented characteristics in intensive care unit admissions for patients with traumatic brain injury in Spain.Frontiers in medicine · 2025Article
- Out-of-Hospital Cardiac Arrest: Does a History of Myocarditis/Perimyocarditis Affect the Outcome? A Swedish Nationwide Study.Journal of the American Heart Association · 2024Article
- Differential Effects of Targeted Temperature Management on Sex-Dependent Outcomes After Experimental Asphyxial Cardiac Arrest.Therapeutic hypothermia and temperature management · 2024Article
- The Interaction Effect of Age, Initial Rhythm, and Location on Outcomes After Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study.Journal of clinical medicine · 2024Article
- Variable importance analysis with interpretable machine learning for fair risk prediction.PLOS digital health · 2024Article
- Post-intensive care syndrome and health-related quality of life in long-term survivors of cardiac arrest: a prospective cohort study.Scientific reports · 2024Article
- Underlying reasons for sex difference in survival following out-of-hospital cardiac arrest: a mediation analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Article
- Sex Differences in Out-of-Hospital Cardiac Arrest Survival Trends.Journal of the American Heart Association · 2024Article
- Predictors, Prevalence, and Clinical Outcomes of Out-of-Hospital Cardiac Arrests in Croatia: A Nationwide Study.Healthcare (Basel, Switzerland) · 2023Article
- Sex Difference on Neurological Outcomes and Post-Cardiac Arrest Care in Out-of-Hospital Cardiac Arrest Patients Treated with Targeted Temperature Management: Post-Hoc Study of a Prospective, Multicenter, Observational Cohort Study.Journal of clinical medicine · 2023Article
- Association between sex and survival after out-of-hospital cardiac arrest: A systematic review and meta-analysis.Journal of the American College of Emergency Physicians open · 2023Article
- Ethnic and sex-based differences in outcomes after out-of-hospital cardiac arrest: a glimpse of the largest municipal healthcare system in the United States.Cardiovascular diagnosis and therapy · 2023Article
- Impact of sex and role of coronary artery disease in out-of-hospital cardiac arrest presenting with refractory ventricular arrhythmias.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Patients who experience out-of-hospital cardiac arrest (OHCA) have unacceptably high mortality rates. It remains unclear whether gender has an association with survival in this regard. Hence, we aimed to investigate the association between gender and survival by conducting a systematic review and meta-analysis. The databases of PubMed, Embase, and Cochrane Database of Systematic Reviews were searched from inception to 17 March, 2020. Studies assessing the association between gender and survival to discharge or 30-day survival after OHCA were included. Two reviewers independently assessed the eligibility of the identified studies. The random-effects model was used to pool data, and the outcome was reported as odds ratios (ORs) and 95% confidence intervals, as the relative measure of association. Twenty-three eligible studies enrolling 897,805 patients were included in this systematic review. Overall, women were older and less likely to experience arrest in public places. When arrest occurred, women had less initial shockable rhythm, were less likely to be witnessed by bystanders, and were less likely provided with CPR compared with men. After admission, women underwent less coronary angiography, percutaneous coronary angiography, and targeted temperature management therapy. Eleven studies with ORs were pooled, showing a significant survival benefit in women (OR = 1.08, p < 0.05, I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.