Evidence map›Paper›PMID 33174148›Full record

ArticleBiological trace element research2021

Expression of DnMTs and MBDs in AlCl

Muhammad Faisal Ikram, Syeda Mehpara Farhat, Aamra Mahboob, Saeeda Baig, Ahmed Yaqinuddin, Touqeer Ahmed

Abstract read
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In one paragraph

Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. MBD1-Mediated SDHD Methylation Aggravates Preeclampsia Progression via Triggering Mitochondrial Dysfunction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Muhammad Faisal IkramDepartment of Anatomy, College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia.
Syeda Mehpara FarhatNeurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan.
Aamra MahboobNeurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan.
Saeeda BaigDepartment of Biochemistry, Ziauddin University, Karachi, Pakistan.
Ahmed YaqinuddinDepartment of Anatomy, College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia.
Touqeer AhmedNeurobiology Laboratory, Department of Healthcare Biotechnology, Atta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology (NUST), Sector H-12, Islamabad, 44000, Pakistan. touqeer.aahmed@gmail.com.ORCID http://orcid.org/0000-0003-0322-8169
Alfaisal University · SANational University of Sciences and Technology · PKNational University of Medical Sciences · PKZiauddin University · PK

Funding

Alfaisal University IRG No. 313091711126
6 · The paper itself

Abstract

Alteration in DNA methylation after aluminum exposure has been shown to contribute in pathogenesis of Alzheimer's disease (AD). This study is aimed to determine the effect of Al exposure (42 and 60 days) on learning and memory and the expression of proteins involved in DNA methylation (MBD1, MBD2, MBD3, MeCP2 (methyl CpG binding protein 2), DnMT1 and DnMT3a). Male BALB/c mice were treated with AlCl

Indexed as

Alzheimer DiseaseHippocampusAluminum ChlorideAnimalsDisease Models, AnimalMaleMiceMice, Inbred BALB CAluminum ChlorideAluminumAlzheimer’s diseaseAnimal modelDNA methylationEnvironmental toxinsEpigenetic alterations

Identifiers

PMID33174148
OpenAlexW3105869999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.