Evidence map›Paper›PMID 33173765›Full record

ArticleFrontiers in chemistry2020

Sensitive LC-MS/MS Method for the Quantification of Macrocyclic Gα

Markus Kuschak, Jonathan G Schlegel, Marion Schneider, Stefan Kehraus, Jan H Voss, Alexander Seidinger, Michaela Matthey, Daniela Wenzel, Bernd K Fleischmann, Gabriele M König and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Markus KuschakPharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany.
Jonathan G SchlegelPharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany.
Marion SchneiderPharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany.
Stefan KehrausInstitute of Pharmaceutical Biology, University of Bonn, Bonn, Germany.
Jan H VossPharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany.
Alexander SeidingerInstitute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Michaela MattheyInstitute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Daniela WenzelInstitute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Bernd K FleischmannInstitute of Physiology I, Life and Brain Center, Medical Faculty, University of Bonn, Bonn, Germany.
Gabriele M KönigInstitute of Pharmaceutical Biology, University of Bonn, Bonn, Germany.
Christa E MüllerPharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany.
University of Bonn · DELife & Brain (Germany) · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cyclic depsipeptide FR900359 (FR) isolated from the plant

Indexed as

drug levelsFR900359Gq inhibitorLC-MS/MSpreclinical experimentsquantificationquantitative analysisYM-254890

Identifiers

PMID33173765
PMCPMC7540253
OpenAlexW3088308702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.