ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020
An Alkaline Based Method for Generating Crystalline, Strong, and Shape Memory Polyvinyl Alcohol Biomaterials.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- Review
- Ion-Driving Polymer Entanglement for Dynamic Organic Phosphorescence.Angewandte Chemie (International ed. in English) · 2026Article
- Dehydration-Driven Self-Curling for Programmable Multimetallic 3D Architectures.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Superior Impact-Resistant Composite Hydrogels Through an Ionic Coupling Strategy.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Freeze-Thaw-Synthesized PVA/Chitosan Hydrogels: Structure-Property Relationships and ANN Modeling of Swelling and Degradation Behaviors.ACS omega · 2026Article
- Biopolymer-Based Active and Intelligent Food Packaging: Recent Advances in Materials, Technologies, and Applications.Polymers · 2026Review
- Polydopamine-Coated Selenium Nanoparticles as a Stable Catalyst for Tunable and Sustained Nitric Oxide Generation.Small science · 2025Article
- A Tailored Hydrogel With Local Glycemia Management, Antioxidant Activity, and Photothermal Antibacterial Properties for Diabetic Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Enhancing auricular reconstruction: A biomimetic scaffold with 3D-printed multiscale porous structure utilizing chondrogenic activity ink.Materials today. Bio · 2025Article
- Research Progress on Using Modified Hydrogel Coatings as Marine Antifouling Materials.Marine drugs · 2024Review
- Effect of Mild Conditions on PVA-Based Theta Gel Preparation: Thermal and Rheological Characterization.International journal of molecular sciences · 2024Article
- Control nucleation for strong and tough crystalline hydrogels with high water content.Nature communications · 2024Article
- Article
- Dual Crosslinked Antioxidant Mixture of Poly(vinyl alcohol) and Cerium Oxide Nanoparticles as a Bioink for 3D Bioprinting.ACS applied nano materials · 2024Review
- Recent Advances in Poly(vinyl alcohol)-Based Hydrogels.Polymers · 2024Review
- Platelet Vesicles Synergetic with Biosynthetic Cellulose Aerogels for Ultra-Fast Hemostasis and Wound Healing.Advanced healthcare materials · 2024Article
- Design and Development of Transient Sensing Devices for Healthcare Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Recent Progress and Challenges of Implantable Biodegradable Biosensors.Micromachines · 2024Review
- Two way workable microchanneled hydrogel suture to diagnose, treat and monitor the infarcted heart.Nature communications · 2024Article
- Rational Design of Multifunctional Hydrogels for Wound Repair.Journal of functional biomaterials · 2023Review
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strong, stretchable, and durable biomaterials with shape memory properties can be useful in different biomedical devices, tissue engineering, and soft robotics. However, it is challenging to combine these features. Semi-crystalline polyvinyl alcohol (PVA) has been used to make hydrogels by conventional methods such as freeze-thaw and chemical crosslinking, but it is formidable to produce strong materials with adjustable properties. Herein, a method to induce crystallinity and produce physically crosslinked PVA hydrogels via applying high-concentration sodium hydroxide into dense PVA polymer is introduced. Such a strategy enables the production of physically crosslinked PVA biomaterial with high mechanical properties, low water content, resistance to injury, and shape memory properties. It is also found that the developed PVA hydrogel can recover 90% of plastic deformation due to extension upon supplying water, providing a strong contraction force sufficiently to lift objects 1100 times more than their weight. Cytocompatibility, antifouling property, hemocompatibility, and biocompatibility are also demonstrated in vitro and in vivo. The fabrication methods of PVA-based catheters, injectable electronics, and microfluidic devices are demonstrated. This gelation approach enables both layer-by-layer and 3D printing fabrications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.